[HTML][HTML] The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks

R Enaud, R Prevel, E Ciarlo, F Beaufils… - Frontiers in cellular …, 2020 - frontiersin.org
The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …

Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations

AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …

Withdrawal of inhaled corticosteroids in COPD: a European Respiratory Society guideline

JD Chalmers, IF Laska, FME Franssen… - European …, 2020 - Eur Respiratory Soc
Inhaled corticosteroids (ICS) combined with bronchodilators can reduce the frequency of
exacerbations in some patients with chronic obstructive pulmonary disease (COPD). There …

Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits

AG Mathioudakis, W Janssens, P Sivapalan… - Thorax, 2020 - thorax.bmj.com
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are associated with a
significant mortality, health and economic burden. Their diagnosis, assessment and …

[HTML][HTML] Predicting and preventing hospital readmission for exacerbations of COPD

CW Kong, TMA Wilkinson - ERJ Open Research, 2020 - Eur Respiratory Soc
More than a third of patients hospitalised for acute exacerbation of COPD are readmitted to
hospital within 90 days. Healthcare professionals and service providers are expected to …

[HTML][HTML] Role of lung microbiome in innate immune response associated with chronic lung diseases

KR Paudel, V Dharwal, VK Patel, I Galvao… - Frontiers in …, 2020 - frontiersin.org
Respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), lung
fibrosis, and lung cancer, pose a huge socio-economic burden on society and are one of the …

[HTML][HTML] Blood eosinophil counts in clinical trials for chronic obstructive pulmonary disease

D Singh, M Bafadhel, CE Brightling… - American journal of …, 2020 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a complex condition with pathophysiology
and clinical characteristics that vary in presence and severity between patients (1). This …

[HTML][HTML] A randomised controlled feasibility trial of E-health application supported care vs usual care after exacerbation of COPD: the RESCUE trial

M North, S Bourne, B Green, AJ Chauhan… - NPJ digital …, 2020 - nature.com
Exacerbations of COPD are one of the commonest causes of admission and readmission to
hospital. The role of digital interventions to support self-management in improving outcomes …

[HTML][HTML] Microbial burden and viral exacerbations in a longitudinal multicenter COPD cohort

J Bouquet, DE Tabor, JS Silver, V Nair… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease
characterized by frequent exacerbation phenotypes independent of disease stage …

[HTML][HTML] Microbiota dysbiosis in lung cancer: evidence of association and potential mechanisms

N Xu, L Wang, C Li, C Ding, C Li, W Fan… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Over the past decade, revolution in microbial research has provided valuable insights into
the function of microbes that inhabit human body. This complex community of microbes …