miRNAs as a novel clinical biomarker and therapeutic targets in polycystic ovary syndrome (PCOS): a review

M Abdalla, H Deshmukh, SL Atkin, T Sathyapalan - Life Sciences, 2020 - Elsevier
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in females of
the reproductive age. PCOS is commonly manifested as ovulatory dysfunction, clinical and …

Involvement of ACE2/Ang-(1-7)/MAS1 axis in the regulation of ovarian function in mammals

K Domińska - International Journal of Molecular Sciences, 2020 - mdpi.com
In addition to the classic, endocrine renin-angiotensin system, local renin-angiotensin
system (RAS) has been documented in many tissues and organs, including the ovaries. The …

Investigation of the effects of vitamin D treatment on the ovarian AMH receptors in a polycystic ovary syndrome experimental model: an ultrastructural and …

Y Kuyucu, L Sencar, Ö Tap, UÖ Mete - Reproductive Biology, 2020 - Elsevier
The aim of this study was to demonstrate the effects of vitamin D treatment on ultrastructural
changes and AMHR2 expression in the ovary in PCOS rat model. A total of 24 female …

Polycystic ovary syndrome: is it androgen or estrogen receptor?

KA Walters - Current Opinion in Endocrine and Metabolic Research, 2020 - Elsevier
Polycystic ovary syndrome (PCOS) is a significant health problem, but unfortunately as the
pathogenesis of PCOS remains unclear there is no cure, and in the absence of mechanistic …

Transgenerational inheritance of reproductive and metabolic phenotypes in PCOS rats

HL Zhang, M Yi, D Li, R Li, Y Zhao… - Frontiers in Endocrinology, 2020 - frontiersin.org
Androgen exposure of female fetuses could be an important factor in the development of
polycystic ovary syndrome (PCOS) in subsequent generations. The present study aimed to …

Deciphering the DNA methylome of polycystic ovary syndrome

Q Tan - Molecular Diagnosis & Therapy, 2020 - Springer
Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of
reproductive age. PCOS is characterized by ovarian dysfunction and metabolic …

[HTML][HTML] The effects of zinc methionine on reproductive and thyroid hormones in rats with polycystic ovarian syndrome

FF Torshizi, M Chamani, HR Khodaei… - Advanced Biomedical …, 2020 - journals.lww.com
Background: Polycystic ovarian syndrome (PCOS) is an endocrine disorder in fertile women,
which seems to be adversely affected by associated thyroid dysfunction. Zinc methionine …

PGK1-AR axis: Benefits of a novel actor in PCOS pathology

T Vezza, M Rocha, VM Víctor - EBioMedicine, 2020 - thelancet.com
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder amongst
women of reproductive age [1]. The National Institutes of Health (NIH) estimates that cases …

Does the observation of lower ratio of anterior anogenital distance and posterior anogenital distance appear in adolescent and remain constant in women diagnosed …

JH Lin, KC Sun, PH Wang - Journal of the Chinese Medical …, 2020 - journals.lww.com
We read the study by Simsir et al1 published in the recent issue of the Journal of the
Chinese Medical Association with interest. The authors pioneered to compare the difference …