Amyloid-β, tau, and the cholinergic system in Alzheimer's disease: Seeking direction in a tangle of clues
A Majdi, S Sadigh-Eteghad… - Reviews in the …, 2020 - degruyter.com
The link between histopathological hallmarks of Alzheimer's disease (AD), ie amyloid
plaques, and neurofibrillary tangles, and AD-associated cognitive impairment, has long …
plaques, and neurofibrillary tangles, and AD-associated cognitive impairment, has long …
Calcium-handling defects and neurodegenerative disease
S Schrank, N Barrington… - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Calcium signaling is critical to neuronal function and regulates highly diverse processes
such as gene transcription, energy production, protein handling, and synaptic structure and …
such as gene transcription, energy production, protein handling, and synaptic structure and …
[HTML][HTML] Therapeutic strategies to target calcium dysregulation in Alzheimer's disease
Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people
worldwide. Unfortunately, none of the current treatments are effective at improving cognitive …
worldwide. Unfortunately, none of the current treatments are effective at improving cognitive …
Dysfunctional proteins in neuropsychiatric disorders: From neurodegeneration to autism spectrum disorders
H Jęśko, M Cieślik, G Gromadzka… - Neurochemistry …, 2020 - Elsevier
Despite fundamental differences in disease course and outcomes, neurodevelopmental
(autism spectrum disorders–ASD) and neurodegenerative disorders (Alzheimer's disease …
(autism spectrum disorders–ASD) and neurodegenerative disorders (Alzheimer's disease …
Advances in the In vitro and In vivo pharmacology of Alpha4beta2 nicotinic receptor positive allosteric modulators
Receptors containing α4 and β2 subunits are a major neuronal nicotinic acetylcholine
receptor (nAChR) subtype in the brain. This receptor plays a critical role in nicotine …
receptor (nAChR) subtype in the brain. This receptor plays a critical role in nicotine …