A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis
A Ramesh, RD Schubert… - Proceedings of the …, 2020 - National Acad Sciences
Central nervous system B cells have several potential roles in multiple sclerosis (MS):
secretors of proinflammatory cytokines and chemokines, presenters of autoantigens to T …
secretors of proinflammatory cytokines and chemokines, presenters of autoantigens to T …
Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation
E Esaulova, C Cantoni, I Shchukina… - Neurology …, 2020 - AAN Enterprises
Objective To identify and characterize myeloid cell populations within the CSF of patients
with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution …
with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution …
Resident plasmacytoid dendritic cells patrol vessels in the naïve limbus and conjunctiva
Plasmacytoid dendritic cells (pDCs) constitute a unique population of bone marrow-derived
cells that play a pivotal role in linking innate and adaptive immune responses. While …
cells that play a pivotal role in linking innate and adaptive immune responses. While …
Cytotoxic activity of CD4 T cells during the early stage of autoimmune neuroinflammation
F Pradella, VO Boldrini, AM Marques, GAD Morais… - BioRxiv, 2020 - biorxiv.org
Pathogenic CD4+ T cells are capable of initiating neuroinflammation in experimental
autoimmune encephalomyelitis (EAE). However, the precise effector mechanism of these …
autoimmune encephalomyelitis (EAE). However, the precise effector mechanism of these …
SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of MS patients
L Ostendorf, P Dittert, R Biesen, A Duchow… - medRxiv, 2020 - medrxiv.org
Objective We aimed to evaluate SIGLEC1 (CD169) as a biomarker in Multiple Sclerosis
(MS) and Neuromyelitis optica spectrum disorder (NMOSD) and to evaluate the specificity of …
(MS) and Neuromyelitis optica spectrum disorder (NMOSD) and to evaluate the specificity of …
Melanocortin Receptor-4 Regulates Expression of Angiostatic Molecules in pDcs Through Nf-κB Signaling
A Abou-Slaybi - 2020 - search.proquest.com
Induction of angiogenesis, the formation of new vessels, is a hallmark and pathology of a
wide range of diseases from cancer to corneal neovascularization. Understanding the …
wide range of diseases from cancer to corneal neovascularization. Understanding the …
[引用][C] Characterization of the myeloid cells in different brain interfaces during neuroinflammation
S Armbruster - 2020 - Dissertation, Universität Freiburg …