Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease

MS Uddin, MT Kabir, D Tewari, B Mathew… - Science of the Total …, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive, chronic and severe neurodegenerative disorder
linked with cognitive and memory impairment that eventually lead to death. There are …

[HTML][HTML] Polyphenolic biflavonoids inhibit amyloid-beta fibrillation and disaggregate preformed amyloid-beta fibrils

EY Choi, SS Kang, SK Lee, BH Han - Biomolecules & therapeutics, 2020 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a devastating neurodegenerative disease and a major cause of
dementia in elderly individuals world-wide. Increased deposition of insoluble amyloid β (Aβ) …

Butein, isoliquiritigenin, and scopoletin attenuate neurodegeneration via antioxidant enzymes and SIRT1/ADAM10 signaling pathway

NH Gay, W Suwanjang, W Ruankham, N Songtawee… - RSC …, 2020 - pubs.rsc.org
Neuronal cell death is a key feature of neurodegenerative disorders such as Parkinson's
and Alzheimer's diseases. Plant polyphenols, namely butein, isoliquiritigenin, and …