Type VI secretion system effector proteins: effective weapons for bacterial competitiveness

RE Hernandez, R Gallegos‐Monterrosa… - Cellular …, 2020 - Wiley Online Library
The Type VI secretion system (T6SS) is a protein translocation nanomachine widespread
among Gram‐negative bacteria and used as a means to deliver effectors directly into target …

The central role of interbacterial antagonism in bacterial life

SB Peterson, SK Bertolli, JD Mougous - Current Biology, 2020 - cell.com
The study of bacteria interacting with their environment has historically centered on
strategies for obtaining nutrients and resisting abiotic stresses. We argue this focus has …

Contact-dependent interbacterial antagonism mediated by protein secretion machines

TA Klein, S Ahmad, JC Whitney - Trends in microbiology, 2020 - cell.com
To establish and maintain an ecological niche, bacteria employ a wide range of pathways to
inhibit the growth of their microbial competitors. Some of these pathways, such as those that …

Good gone bad: one toxin away from disease for Bacteroides fragilis

E Valguarnera, JB Wardenburg - Journal of molecular biology, 2020 - Elsevier
The human gut is colonized by hundreds of trillions of microorganisms whose acquisition
begins during early infancy. Species from the Bacteroides genus are ubiquitous …

Role of carbon monoxide in host–gut microbiome communication

CP Hopper, LK De La Cruz, KV Lyles… - Chemical …, 2020 - ACS Publications
Nature is full of examples of symbiotic relationships. The critical symbiotic relation between
host and mutualistic bacteria is attracting increasing attention to the degree that the gut …

Immune-microbiota interplay and colonization resistance in infection

A Leshem, T Liwinski, E Elinav - Molecular cell, 2020 - cell.com
Commensal microbial communities inhabit biological niches in the mammalian host, where
they impact the host's physiology through induction of" colonization resistance" against …

The evolution of the type VI secretion system as a disintegration weapon

WPJ Smith, A Vettiger, J Winter, T Ryser… - PLoS …, 2020 - journals.plos.org
The type VI secretion system (T6SS) is a nanomachine used by many bacteria to drive a
toxin-laden needle into other bacterial cells. Although the potential to influence bacterial …

Developmental, Dietary, and Geographical Impacts on Gut Microbiota of Red Swamp Crayfish (Procambarus clarkii)

Z Zhang, J Liu, X Jin, C Liu, C Fan, L Guo, Y Liang… - Microorganisms, 2020 - mdpi.com
Red swamp crayfish (Procambarus clarkii) breeding is an important economic mainstay in
Hubei province, China. However, information on the gut microbiota of the red swamp …

[HTML][HTML] Defending against the type six secretion system: beyond immunity genes

SJ Hersch, K Manera, TG Dong - Cell Reports, 2020 - cell.com
The bacterial type six secretion system (T6SS) delivers toxic effector proteins into
neighboring cells, but bacteria must protect themselves against their own T6SS. Immunity …

Causalities of war: the connection between type VI secretion system and microbiota

LP Allsopp, P Bernal, LM Nolan… - Cellular …, 2020 - Wiley Online Library
Microbiota niches have space and/or nutrient restrictions, which has led to the coevolution of
cooperation, specialisation, and competition within the population. Different animal and …