The use of the central vein sign in the diagnosis of multiple sclerosis: a systematic review and meta-analysis

M Castellaro, A Tamanti, AI Pisani, FB Pizzini… - Diagnostics, 2020 - mdpi.com
Background: The central vein sign (CVS) is a radiological feature proposed as a multiple
sclerosis (MS) imaging biomarker able to accurately differentiate MS from other white matter …

Ultra-high-field 7-T MRI in multiple sclerosis and other demyelinating diseases: from pathology to clinical practice

N Bruschi, G Boffa, M Inglese - European radiology experimental, 2020 - Springer
Magnetic resonance imaging (MRI) is essential for the early diagnosis of multiple sclerosis
(MS), for investigating the disease pathophysiology, and for discriminating MS from other …

Paramagnetic rim lesions are specific to multiple sclerosis: an international multicenter 3T MRI study

P Maggi, P Sati, G Nair, ICM Cortese… - Annals of …, 2020 - Wiley Online Library
In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on
magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports …

Value of 3T susceptibility-weighted imaging in the diagnosis of multiple sclerosis

MA Clarke, D Pareto… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Previous studies have suggested that the central vein sign
and iron rims are specific features of MS lesions. Using 3T SWI, we aimed to compare the …

The “central vein sign” in patients with diagnostic “red flags” for multiple sclerosis: a prospective multicenter 3T study

P Maggi, M Absinta, P Sati, G Perrotta… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: The central vein sign (CVS) has been shown to help in the differential
diagnosis of multiple sclerosis (MS), but most prior studies are retrospective. Objectives: To …

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis

P Maggi, MJ Fartaria, J Jorge, F La Rosa… - NMR in …, 2020 - Wiley Online Library
The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS)
diagnosis, but its application in clinical routine is limited by inter‐rater variability and the …

Visualizing the central nervous system: imaging tools for multiple sclerosis and neuromyelitis optica spectrum disorders

J Kuchling, F Paul - Frontiers in Neurology, 2020 - frontiersin.org
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are
autoimmune central nervous system conditions with increasing incidence and prevalence …

Increased incidence of Susac syndrome: a case series study

A Wilf-Yarkoni, O Elkayam, O Aizenstein, Y Oron… - BMC neurology, 2020 - Springer
Abstract Background Susac syndrome (SuS) is a rare condition characterized by a clinical
triad of sensorineural hearing loss, branch artery occlusion and encephalopathy. This study …

Iron rims as an imaging biomarker in MS: A systematic mapping review

AI AlTokhis, AM AlOtaibi, GA Felmban… - Diagnostics, 2020 - mdpi.com
Background: Multiple sclerosis (MS) is an autoimmune, inflammatory, demyelinating and
degenerative disease of the central nervous system (CNS). To date, there is no definitive …

CNS vasculopathies: Challenging mimickers of primary angiitis of the central nervous system

TA Cho, A Jones - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
Primary angiitis of the central nervous system (CNS) is an inflammatory vasculopathy
affecting the brain and spinal cord. It is a difficult diagnosis to make because of its insidious …