Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors

MH El‐Hamamsy, NA Sharafeldin… - Archiv der …, 2020 - Wiley Online Library
Lung, colorectal, and breast cancers are the top three types of cancer by incidence and are
responsible for one‐third of the cancer incidence and mortality. A series of 18 3, 4 …

[HTML][HTML] Monastrol derivatives: in silico: and: in vitro: cytotoxicity assessments

Z Bidram, H Sirous, GA Khodarahmi… - Research in …, 2020 - journals.lww.com
Monastrol derivatives: in silico: and: in vitro: cytotoxicit... : Research in Pharmaceutical Sciences
Monastrol derivatives: in silico: and: in vitro: cytotoxicity assessments : Research in …

Stereochemistry of the α-carbon in the benzylic modifying moiety attached at the C-5 end of thymidine affects the potency of a newly identified anti-cancer lead …

AP Bercz, WA McClure, M English, MW Keebaugh… - Tetrahedron, 2020 - Elsevier
The bioactivity of antimetabolites is connected to molecular recognition by the target
proteins, which makes the stereochemical configuration of the chiral centers in these …