Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

Titanium implants have been widely used in bone tissue engineering for decades. However,
orthopedic implant-associated infections increase the risk of implant failure and even lead to …

Pathogenic bacteria infection is a major public health problem due to the high morbidity and
mortality rates, as well as the increased expenditure on patient management. Although there …

Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …

Quorum sensing (QS), a microbial cell-to-cell communication process, dynamically regulates
a variety of metabolism and physiological activities. In this review, we provide an update on …

Titanium (Ti) and its alloys are commonly used in medical devices. However, biomaterial-
associated infections such as peri-implantitis and prosthetic joint infections are devastating …

Natural products have historically been a rich source of diverse chemical matter with
numerous biological activities, and have played an important role in drug discovery in many …

Background The use of implanted medical devices is associated with a small but clinically
important risk of foreign body infection. A key question is: why do some patients develop …