MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

Intermediate filaments are major components of the cytoskeleton. Desmin and synemin,
cytoplasmic intermediate filament proteins and A-type lamins, nuclear intermediate filament …

The identification of the molecular causes and subsequent insight into the molecular
mechanisms of DCM is expanding our understanding of DCM pathogenesis and highlights …

Introduction and objectives According to sudden cardiac death guidelines, an implantable
cardioverter-defibrillator (ICD) should be considered in patients with LMNA-related dilated …

Background Truncating variants in titin (TTNtv) are the most common cause of dilated
cardiomyopathy (DCM). We evaluated the genotype-phenotype correlation in TTNtv-DCM …

Background LMNA-related muscular dystrophy is caused by mutations in LMNA gene. We
aimed to identify genetic variations and clinical features in a large cohort of Chinese patients …

Genetics has played an important role in the understanding of different cardiomyopathies,
and the field of heart failure (HF) genetics is progressing rapidly. Much research has also …

Dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders
characterized by ventricular dilation and depressed myocardial performance in the absence …

Dilated cardiomyopathy (DCM) is a cardiovascular disease of genetic aetiology that causes
substantial morbidity and mortality, and presents considerable opportunity for disease …

Dilated cardiomyopathy (DCM) is the third most common cause of heart failure. The
multidisciplinary nature of testing—involving genetics, imaging, or cardiovascular …