Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …

Invasive infection caused by Candida species is a condition associated with medical
progress. It is a common health care–associated infection (HAI), and is widely recognized as …

Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of …

Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …

Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …