[HTML][HTML] New frontiers in psoriatic disease research, part I: genetics, environmental triggers, immunology, pathophysiology, and precision medicine

D Yan, JE Gudjonsson, S Le, E Maverakis… - Journal of Investigative …, 2021 - Elsevier
Psoriasis is a chronic inflammatory condition characterized by systemic immune
dysregulation. Over the past several years, advances in genetics, microbiology …

Exploring the diverse immune and genetic landscape of psoriatic arthritis

B Batko - Journal of Clinical Medicine, 2021 - mdpi.com
Psoriatic arthritis (PsA) is characterized by delays in diagnosis and modest effect of
treatment in terms of joint response. An understanding of molecular pathomechanisms may …

Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals

H Xu, Q Zhen, M Bai, L Fang, Y Zhang, B Li… - Genome …, 2021 - genome.cshlp.org
Protein-truncating variants (PTVs) have important impacts on phenotype diversity and
disease. However, their population genetics characteristics in more globally diverse …

Proteomic analysis of psoriatic skin lesions in a Chinese population

W Wang, Q Xu, B Li, H Li, S Shen, J Wu, H Ge… - Journal of …, 2021 - Elsevier
Psoriasis is a chronic skin disorder with undefined pathogenesis. Several biomarkers for this
disease have been identified by proteomic analysis. We explored the whole-proteomic …