Glaucoma in adults—screening, diagnosis, and management: a review

JD Stein, AP Khawaja, JS Weizer - Jama, 2021 - jamanetwork.com
Importance Glaucoma is the most common cause of irreversible blindness worldwide. Many
patients with glaucoma are asymptomatic early in the disease course. Primary care …

Therapeutic drugs and devices for tackling ocular hypertension and glaucoma, and need for neuroprotection and cytoprotective therapies

NA Sharif - Frontiers in pharmacology, 2021 - frontiersin.org
Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

Primary open-angle glaucoma preferred practice pattern®

SJ Gedde, K Vinod, MM Wright, KW Muir, JT Lind… - Ophthalmology, 2021 - Elsevier
Background Primary open angle glaucoma (POAG) is a chronic, progressive ocular disease
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …

Twelve-month efficacy and safety of omidenepag isopropyl, a selective EP2 agonist, in open-angle glaucoma and ocular hypertension: the RENGE study

M Aihara, F Lu, H Kawata, A Iwata… - Japanese Journal of …, 2021 - Springer
Purpose To assess the long-term safety and efficacy of omidenepag isopropyl (OMDI)
0.002%(a first-in-class, selective, non-prostaglandin, prostanoid EP2 receptor agonist) …

Association between daily niacin intake and glaucoma: National Health and Nutrition Examination Survey

T Taechameekietichai, S Chansangpetch… - Nutrients, 2021 - mdpi.com
Background and Aims: To determine the relationship between dietary intake of niacin and
glaucoma using the data from the 2005 to 2008 National Health and Nutrition Examination …

Primary open-angle glaucoma suspect preferred practice pattern®

SJ Gedde, JT Lind, MM Wright, PP Chen, KW Muir… - Ophthalmology, 2021 - Elsevier
Background A diagnosis of primary open angle glaucoma (POAG) suspect is established by
the presence of consistently elevated intraocular pressure (IOP), also know as ocular …

Looking into the future: Gene and cell therapies for glaucoma

AM Komáromy, KL Koehl, SA Park - Veterinary ophthalmology, 2021 - Wiley Online Library
Glaucoma is a complex group of optic neuropathies that affects both humans and animals.
Intraocular pressure (IOP) elevation is a major risk factor that results in the loss of retinal …

Carotenoids in the management of glaucoma: A systematic review of the evidence

DW Lem, DL Gierhart, PG Davey - Nutrients, 2021 - mdpi.com
Primary open-angle glaucoma (POAG) remains a leading cause of irreversible blindness
globally. Recent evidence further substantiates sustained oxidative stress, and …

Impact of intraocular pressure control on rates of retinal nerve fiber layer loss in a large clinical population

AA Jammal, AC Thompson, EB Mariottoni, T Estrela… - Ophthalmology, 2021 - Elsevier
Purpose To investigate the impact of intraocular pressure (IOP) control on rates of change of
spectral-domain OCT (SD-OCT) retinal nerve fiber layer (RNFL) thickness in a large clinical …

Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT

AJ King, G Fernie, J Hudson… - Health …, 2021 - research-repository.st-andrews.ac …
Background: Patients diagnosed with advanced primary open-angle glaucoma are at a high
risk of lifetime blindness. Uncertainty exists about whether primary medical management …