Favipiravir is found to show excellent in-vitro inhibition activity against Nipah virus. To
explore the structure–property relationship of Favipiravir, in silico designing of a series of …

In this work, the density functional theory with B3LYP hybrid functional was employed to
calculate quantities useful for estimating the behavior of pyridine, pyrazine and their …

Drug Discovery with Privileged Building Blocks traces back PharmaBlock's founding
philosophy of designing privileged building blocks. High-quality building blocks are crucial …

The progress made during the past three decades on the synthesis and application of stable
nitroxide free radicals has facilitated understanding of the structure and function of …

The lateral metalation-electrophilic trapping reaction of alkyl-substituted pyrazines has
always been challenging and poorly regioselective, with the corresponding derivatives often …

We report a one-step method for the synthesis of alkoxy substituted pyrazine derivatives.
The process makes use of an improved acid-mediated coupling reaction to afford the …