Despite mass drug administration programmes with praziquantel, the prevalence of
schistosomiasis remains high. A vaccine is urgently needed to control transmission of this …

Malaria reflects not only a state of immune activation, but also a state of general immune
defect or immunosuppression, of complex etiology that can last longer than the actual …

Malaria can cause life-threatening complications which are often associated with
inflammatory reactions. More subtle, but also contributing to the burden of disease are …

Abstract According to World Malaria Report 2020, the rate of decline in malaria case
incidence and deaths caused by malaria has ceased in latter half of the past decade …

Introduction Malaria has been a significant threat to human health throughout history. As an
effective vaccine against malaria is not available yet vector control measures like the use of …

Plasmodium falciparum (Pf) malaria causes high rates of morbidity and mortality and lacks a
sufficiently effective vaccine. Clinical immunity develops in residents of malaria endemic …

Malaria is still a major global challenge, particularly in sub-Saharan Africa where nearly two-
thirds of the global malaria cases are reported annually. The majority of the cases are …

Background. Recent studies have shown that the inflammatory process, including the
biomarker production, and the intense activation of innate immune responses are greater in …

Driciru et al. Immunological Considerations for Schistosoma-Vaccine Development
implementation policies. Besides well-designed studies in different target populations using …

Malaria remains a global health burden, inflicting millions of people worldwide. Both CD4+ T
cell-and humoral-mediated immunity are crucial to help control parasites in vivo. The …