Low carbohydrates diets (LCDs), which provide 20–120 g of carbohydrates per day, have
long been used as therapeutic options in the treatment of severe obesity, type 2 diabetes …

Solute carriers form one of three major superfamilies of membrane transporters in humans,
and include uniporters, exchangers and symporters. Following several decades of …

Metabolism in acute myeloid leukemia (AML) cells is dependent primarily on oxidative
phosphorylation. However, in order to sustain their high proliferation rate and metabolic …

The current study was conducted to investigate the therapeutic effects of atorvastatin (ATV)
and resveratrol (RVT) in sole and simultaneous forms of administration against the …

SARS-CoV-2 viral contagion has given rise to a worldwide pandemic. Although most
children experience minor symptoms from SARS-CoV-2 infection, some have severe …

Introduction Cancer of unknown primary origin (CUP) is defined as metastatic cancer without
identification of the primary site. Considering that only 15–20% of patients with CUP show a …

Background Cholangiocarcinoma (CCA) is a malignant tumor of the digestive system, with
occult onset in the early stage, a high degree of malignancy in the late stage, and poor …

目的: 靶向治疗晚期肾透明细胞癌远未达到临床预想的效果. 如何能寻找一种能够预测其治疗
效果的生物标志物成为迫切需要解决的问题. 本课题主要研究单羧酸转运蛋白MCT1 和MCT4 …

Therapeutic interest in targeting cancer metabolism has become emerging in recent years.
However, a very few numbers of molecules has been identified as a potential modulator of …

Cancer is a complex disease that represents a vast problem worldwide due to its high
incidence and mortality, being the second leading cause of death globally. Even with the …