Major depressive disorder: advances in neuroscience research and translational applications
Z Li, M Ruan, J Chen, Y Fang - Neuroscience bulletin, 2021 - Springer
Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …
psychiatric disorders with a high economic burden. The etiology of depression is still not …
Smartphone-based ecological momentary assessment of well-being: A systematic review and recommendations for future studies
Feelings of well-being and happiness fluctuate over time and contexts. Ecological
Momentary Assessment (EMA) studies can capture fluctuations in momentary behavior, and …
Momentary Assessment (EMA) studies can capture fluctuations in momentary behavior, and …
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study
Importance Most previous genome-wide association studies (GWAS) of depression have
used data from individuals of European descent. This limits the understanding of the …
used data from individuals of European descent. This limits the understanding of the …
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other
gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable …
gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable …
Topologically associating domain boundaries that are stable across diverse cell types are evolutionarily constrained and enriched for heritability
E McArthur, JA Capra - The American Journal of Human Genetics, 2021 - cell.com
Topologically associating domains (TADs) are fundamental units of three-dimensional (3D)
nuclear organization. The regions bordering TADs—TAD boundaries—contribute to the …
nuclear organization. The regions bordering TADs—TAD boundaries—contribute to the …
Life satisfaction and subsequent physical, behavioral, and psychosocial health in older adults
Policy Points Several intergovernmental organizations (Organisation for Economic Co‐
operation and Development, World Health Organization, United Nations) are urging …
operation and Development, World Health Organization, United Nations) are urging …
Resource profile and user guide of the Polygenic Index Repository
Polygenic indexes (PGIs) are DNA-based predictors. Their value for research in many
scientific disciplines is growing rapidly. As a resource for researchers, we used a consistent …
scientific disciplines is growing rapidly. As a resource for researchers, we used a consistent …
The genetic basis of major depression
KM Kendall, E Van Assche, TFM Andlauer… - Psychological …, 2021 - cambridge.org
Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …
SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
Local genetic correlation quantifies the genetic similarity of complex traits in specific
genomic regions. However, accurate estimation of local genetic correlation remains …
genomic regions. However, accurate estimation of local genetic correlation remains …