[HTML][HTML] Polyphenols from food by-products: An alternative or complementary therapy to IBD conventional treatments
AP da Fonseca Machado, MV Geraldi… - Food research …, 2021 - Elsevier
Inflammatory bowel diseases (IBD) are illnesses characterized by chronic intestinal
inflammation and microbial dysbiosis that have emerged as a public health challenge …
inflammation and microbial dysbiosis that have emerged as a public health challenge …
[HTML][HTML] Ozone-induced oxidative stress, neutrophilic airway inflammation, and glucocorticoid resistance in asthma
Despite recent advances in using biologicals that target Th2 pathways, glucocorticoids form
the mainstay of asthma treatment. Asthma morbidity and mortality remain high due to the …
the mainstay of asthma treatment. Asthma morbidity and mortality remain high due to the …
Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I
M Sokolowska, GE Rovati, Z Diamant, E Untersmayr… - Allergy, 2021 - Wiley Online Library
Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes,
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …
Nuclear receptors in podocyte biology and glomerular disease
S Agrawal, JC He, PL Tharaux - Nature Reviews Nephrology, 2021 - nature.com
Nuclear receptors have a broad spectrum of biological functions in normal physiology and in
the pathology of various diseases, including glomerular disease. The primary therapies for …
the pathology of various diseases, including glomerular disease. The primary therapies for …
[HTML][HTML] Pharmacological rationale for targeting IL-17 in asthma
SF Rahmawati, M Te Velde, HAM Kerstjens… - Frontiers in …, 2021 - frontiersin.org
Asthma is a respiratory disease that currently affects around 300 million people worldwide
and is defined by coughing, shortness of breath, wheezing, mucus overproduction, chest …
and is defined by coughing, shortness of breath, wheezing, mucus overproduction, chest …
[HTML][HTML] Mifepristone (RU486) inhibits dietary lipid digestion by antagonizing the role of glucocorticoid receptor on lipase transcription
P Ma, Y Zhang, Q Liang, Y Yin, S Wang, R Han, C Huo… - Iscience, 2021 - cell.com
Lipid digestion and absorption are tightly regulated to cope with metabolic demands among
tissues. How these processes are coordinated is not well characterized. Here, we found that …
tissues. How these processes are coordinated is not well characterized. Here, we found that …
The role of systemic corticosteroids in severe asthma and new evidence in their management and tapering
F Menzella, G Ghidoni, M Fontana… - Expert review of …, 2021 - Taylor & Francis
Introduction Based on the latest literature evidence, between 30% and 60% of adults with
severe refractory asthma (SRA) are systemic corticosteroid (SCS) dependent. There are …
severe refractory asthma (SRA) are systemic corticosteroid (SCS) dependent. There are …
SIRT1 single-nucleotide polymorphisms are associated with corticosteroid sensitivity in primary immune thrombocytopenia patients
S Wang, X Zhang, S Leng, Y Zhang, J Li, J Peng… - Annals of …, 2021 - Springer
Background Primary immune thrombocytopenia (ITP) is an autoimmune disorder
characterized by decreased platelet count. While corticosteroids are a useful first-line …
characterized by decreased platelet count. While corticosteroids are a useful first-line …
[HTML][HTML] Nuclear receptors in asthma: empowering classical molecules against a contemporary ailment
D Tiwari, P Gupta - Frontiers in immunology, 2021 - frontiersin.org
The escalation in living standards and adoption of 'Western lifestyle'has an allied effect on
the increased allergy and asthma burden in both developed and developing countries …
the increased allergy and asthma burden in both developed and developing countries …
Association of glucocorticoid receptor gene NR3C1 (Tth111I, Bcli) polymorphisms with asthma children in Iraq
HM Al-Shami, SJ Al-Awadi… - Annals of the Romanian …, 2021 - annalsofrscb.ro
Glucocorticoids in-general are considered the most powerful and efficient treatment for
asthma. The following investigation was aimed to study the effect of the glucocorticoid …
asthma. The following investigation was aimed to study the effect of the glucocorticoid …