[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …

Anti-inflammatory effects of curcumin in the inflammatory diseases: status, limitations and countermeasures

Y Peng, M Ao, B Dong, Y Jiang, L Yu… - Drug design …, 2021 - Taylor & Francis
Curcumin is a natural compound with great potential for disease treatment. A large number
of studies have proved that curcumin has a variety of biological activities, among which anti …

A triple‐blind, placebo‐controlled, randomized clinical trial to evaluate the effect of curcumin‐containing nanomicelles on cellular immune responses subtypes and …

M Hassaniazad, E Eftekhar… - Phytotherapy …, 2021 - Wiley Online Library
In COVID‐19 patients, cytokine storm due to excessive immune responses can cause
severe complications. In this study, we investigated the effect of curcumin nanomicelles on …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

Curcumin as an adjuvant to cancer immunotherapy

S Paul, G Sa - Frontiers in oncology, 2021 - frontiersin.org
The components of the immune system play a very sincere and crucial role in combating
tumors. However, despite their firm efforts of elimination, tumor cells cleverly escape the …

Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation …

Y Zheng, J Zhang, Y Zhao, Y Zhang, X Zhang… - International …, 2021 - Elsevier
Background Chronic cerebral hypoperfusion (CCH) is regarded as a high-risk factor for
cognitive decline in vascular dementia (VaD). We have previously shown that diabetes …

Antioxidant and anti-inflammatory response to curcumin supplementation in hemodialysis patients: a randomized, double-blind, placebo-controlled clinical trial

HCN Rodrigues, TFP Martins, CC Braga… - Clinical nutrition …, 2021 - Elsevier
Background and objectives Hemodialysis (HD) patients are vulnerable to malnutrition and
cardiovascular complications due to many factors, including oxidative stress and …

Curcumin: a dietary phytochemical for targeting the phenotype and function of dendritic cells

K Rahimi, K Hassanzadeh… - Current medicinal …, 2021 - ingentaconnect.com
Dendritic cells (DCs) are the most powerful antigen-presenting cells which link the innate
and adaptive immune responses. Depending on the context, DCs initiate the immune …

Global survey of medicinal plants during lactation and postpartum recovery: Evolutionary perspectives and contemporary health implications

L Sibeko, T Johns - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Cross-cultural comparison of plants used during lactation
and the postpartum period offers insight into a largely overlooked area of …

Evaluation of the effect of curcumin on pneumonia: A systematic review of preclinical studies

B Alikiaii, M Bagherniya, G Askari… - Phytotherapy …, 2021 - Wiley Online Library
Pneumonia is a major cause of morbidity and mortality worldwide and causes a significant
burden on the healthcare systems. Curcumin is a natural phytochemical with anti …