Unique Positive Cooperativity Between the β-Arrestin–Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor

B Pani, S Ahn, PK Rambarat, S Vege, AW Kahsai… - Molecular …, 2021 - ASPET
Among β-blockers that are clinically prescribed for heart failure, carvedilol is a first-choice
agent with unique pharmacological properties. Carvedilol is distinct from other β-blockers in …