[HTML][HTML] Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

[HTML][HTML] Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Antibiofilm activity of host defence peptides: Complexity provides opportunities

REW Hancock, MA Alford, EF Haney - Nature Reviews Microbiology, 2021 - nature.com
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation

Y Jiang, Y Chen, Z Song, Z Tan, J Cheng - Advanced Drug Delivery …, 2021 - Elsevier
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

Defensins: The natural peptide antibiotic

X Gao, J Ding, C Liao, J Xu, X Liu, W Lu - Advanced drug delivery reviews, 2021 - Elsevier
Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …

An ancient antimicrobial protein co-opted by a fungal plant pathogen for in planta mycobiome manipulation

NC Snelders, GC Petti… - Proceedings of the …, 2021 - National Acad Sciences
Microbes typically secrete a plethora of molecules to promote niche colonization. Soil-
dwelling microbes are well-known producers of antimicrobials that are exploited to …

Dealing with MDR bacteria and biofilm in the post-antibiotic era: Application of antimicrobial peptides-based nano-formulation

X Song, P Liu, X Liu, Y Wang, H Wei, J Zhang… - Materials Science and …, 2021 - Elsevier
The rapid development of multidrug-resistant (MDR) bacteria due to the improper and
overuse of antibiotics and the ineffective performance of antibiotics against the difficult-to …

[HTML][HTML] The effect of the antimicrobial peptide plectasin on the growth performance, intestinal health, and immune function of yellow-feathered chickens

X Zhang, Q Zhao, L Wen, C Wu, Z Yao… - Frontiers in Veterinary …, 2021 - frontiersin.org
The goal of the study was to test the effects of an antibiotic substitute, plectasin, on the
growth performance, immune function, intestinal morphology and structure, intestinal …

[HTML][HTML] Tick peptides evoke itch by activating MrgprC11/MRGPRX1 to sensitize TRPV1 in pruriceptors

X Li, H Yang, Y Han, S Yin, B Shen, Y Wu, W Li… - Journal of Allergy and …, 2021 - Elsevier
Background Tick bites severely threaten human health because they allow the transmission
of many deadly pathogens, including viruses, bacteria, protozoa, and helminths. Pruritus is a …