[HTML][HTML] The function of cumulus cells in oocyte growth and maturation and in subsequent ovulation and fertilization

B Turathum, EM Gao, RC Chian - Cells, 2021 - mdpi.com
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in
mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the …

Metalloproteases in gonad formation and ovulation

Y Zhu - General and comparative endocrinology, 2021 - Elsevier
Abstract Changes in expression or activation of various metalloproteases including matrix
metalloproteases (Mmp), a disintegrin and metalloprotease (Adam) and a disintegrin and …

Identification of novel ADAMTS1, ADAMTS4 and ADAMTS5 cleavage sites in versican using a label-free quantitative proteomics approach

DR Martin, S Santamaria, CD Koch, J Ahnström… - Journal of …, 2021 - Elsevier
The chondroitin sulfate proteoglycan versican is important for embryonic development and
several human disorders. The versican V1 splice isoform is widely expressed and cleaved …

Granulosa cell genes that regulate ovarian follicle development beyond the antral stage: The role of estrogen receptor β

VP Chakravarthi, A Ratri, S Masumi, S Borosha… - Molecular and cellular …, 2021 - Elsevier
Follicle development beyond the preantral stage is dependent on gonadotropins. FSH
signaling is crucial for the advancement of preantral follicles to the antral stage, and LH …

Alteration in angiogenic potential of granulosa-lutein cells and follicular fluid contributes to luteal defects in polycystic ovary syndrome

K Patil, I Hinduja, S Mukherjee - Human Reproduction, 2021 - academic.oup.com
STUDY QUESTION Is angiogenic potential of follicular fluid (FF) and granulosa-lutein cells
(GLCs) altered in polycystic ovary syndrome (PCOS) and does it play a role in corpus luteum …

[HTML][HTML] Expression level of ADAMTS1 in granulosa cells of PCOS patients is related to granulosa cell function, oocyte quality, and embryo development

G Yang, G Yao, Z Xu, H Fan, X Liu, J He… - Frontiers in cell and …, 2021 - frontiersin.org
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) is an
extracellular matrix metalloproteinase that plays an important role in the process of …

Ovulation is Inhibited by an Environmentally Relevant Phthalate Mixture in Mouse Antral Follicles In Vitro

KL Land, ME Lane, AC Fugate… - Toxicological …, 2021 - academic.oup.com
Phthalates are solvents and plasticizers found in consumer products including cosmetics,
food/beverage containers, housing materials, etc. Phthalates are known endocrine …

ADAMTS1 is regulated by the EP4 receptor in the zebrafish ovary

SJC Baker, G Van Der Kraak - General and Comparative Endocrinology, 2021 - Elsevier
Prostaglandins (PGs) are a class of fatty-acid derived hormones that are essential in
ovulation of teleosts, but their exact role remains unknown. One putative target of PGs in …

[HTML][HTML] ADAMTS proteoglycanases downregulation with impaired oocyte quality in PCOS

S Gohari taban, I Amiri, M Saidijam… - … of Endocrinology and …, 2021 - SciELO Brasil
Objective: A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
and ADAMTS-5 normal expression levels are essential for ovulation and subsequent …

Transcriptome profiling of in vitro-matured oocytes from a korean native cow (hanwoo) after cysteamine supplementation

MMR Chowdhury, J Park, F Afrin, YG Ko… - Animal …, 2021 - Taylor & Francis
This study elucidated the molecular markers that decrease oocyte quality during in vitro
culture, restricting optimal developmental potential. Here, we evaluated the transcriptomic …