Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

Population aging is occurring rapidly worldwide, challenging the global economy and
healthcare services. Brain aging is a significant contributor to various age-related …

Inflammatory responses, characterized by the overproduction of numerous proinflammatory
mediators by immune cells, is essential to protect the host against invading pathogens …

Drug-induced nephrotoxicity (DIN) is a major cause of kidney damage and is associated
with high mortality and morbidity, which limits the clinical use of certain therapeutic or …

Head and neck squamous cell carcinoma (HNSCC), one of the most common malignancies
worldwide, often has a poor prognosis due to the associated metastasis and …

Background Although the etiopathogenesis of alopecia areata (AA) is still unclear,
inflammation, oxidative stress, and subsequent DNA damage might be considered role …

Objectives: The roles of innate immunity including macrophages in radiation-induced
abscopal effect (RIAE) are ambiguous. In this study, we evaluated the role of macrophage in …

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with poor
prognosis and overall survival. Clinical investigations show that chronic stress is commonly …

Noise-induced hearing loss (NIHL) is a common inner ear disease but has complex
pathological mechanisms, one of which is increased oxidative stress in the cochlea. The …