Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

This article is a review of approaches to treatment of low and high-grade prostate cancer
including a discussion of active treatment vs. active surveillance for patients with low-grade …

Context Genomic testing is becoming increasingly important in patients with advanced
prostate cancer (PC) and is being incorporated in clinical practice to guide treatment …

Introduction Our understanding of risk factors for COVID‑19, including pre-existing medical
conditions and genetic variations, is limited. To what extent the pre-existing clinical condition …

A promise of genomics in precision medicine is to provide individualized genetic risk
predictions. Polygenic risk scores (PRS), computed by aggregating effects from many …

Prostate cancer (PCa) is the second most frequently diagnosed malignancy and the second
leading cause of death in men worldwide, after adjusting for age. According to the …

Simple Summary The potential importance of germline genetic variation for identifying men
at increased risk of prostate cancer has become increasingly recognised in recent years. We …

Background Understanding the genetic architecture of temperature adaptation is key for
characterizing and predicting the effect of climate change on natural populations. One …

Prenatal exposure to bisphenol A (BPA) is associated with numerous adverse health
outcomes among offspring. Although DNA methylation is considered one of the underlying …

Simple Summary Advances in our understanding of the molecular basis of prostate cancer
have resulted in the discovery of a subset of patients harboring germline variants that places …