Background Originally studied as a mechanism to understand eclampsia-related deaths
during pregnancy, fetal cells in maternal blood have more recently garnered attention as a …

Disclosed here is a composition for isolating nucleic acids from a biological sample,
comprising a chaotropic com pound and a solvent, wherein the solvent comprises a nitrile …

The invention provides methods for simultaneously amplifying multiple nucleic acid regions
of interest in one reaction volume as well as methods for selecting a library of primers for use …

Disclosed herein is a system and method for increasing the fidelity of measured genetic
data, for making allele calls, and for determining the state of aneuploidy, in one or a small …

Disclosed herein is a system and method for increasing the fidelity of measured genetic
data, for making allele calls, and for determining the state of aneuploidy, in one or a small …

Nowadays, millions of individuals suffer from dominant or recessive genetic mutations that
cause highly severe or life-threatening phenotypes in the world. In total, the Online …

The studies conferred in this thesis were performed to establish an appropriate PCR
methodology to target sex-chromosome specific genes for prenatal fetal sex determination in …

The possibility of performing an early noninvasive prenatal diagnosis on fetal cells isolated
from maternal peripheral blood is an important goal for modern obstetric care. A recent …

BACKGROUND: Originally studied as a mechanism to understand eclampsia-related deaths
during pregnancy, fetal cells in maternal blood have more recently garnered attention as a …

Methods, systems, and apparatus determine whether a first chromosomal region exhibits a
deletion or an amplification associated with cancer in a sample from a subject (eg, where the …