Biofilms in diabetic foot ulcers: impact, risk factors and control strategies

AC Afonso, D Oliveira, MJ Saavedra, A Borges… - International journal of …, 2021 - mdpi.com
Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections

G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

Mixed biofilms of pathogenic Candida-bacteria: regulation mechanisms and treatment strategies

F Khan, NI Bamunuarachchi, DTN Pham… - Critical reviews in …, 2021 - Taylor & Francis
Mixed-species biofilm is one of the most frequently recorded clinical problems. Mixed
biofilms develop as a result of interactions between microorganisms of a single or multiple …

Inhibitory Effects of Lipopeptides and Glycolipids on C. albicans–Staphylococcus spp. Dual-Species Biofilms

C Ceresa, M Rinaldi, F Tessarolo, D Maniglio… - Frontiers in …, 2021 - frontiersin.org
Microbial biofilms strongly resist host immune responses and antimicrobial treatments and
are frequently responsible for chronic infections in peri-implant tissues. Biosurfactants (BSs) …

Peptides and dendrimers: How to combat viral and bacterial infections

A Falanga, V Del Genio, S Galdiero - Pharmaceutics, 2021 - mdpi.com
The alarming growth of antimicrobial resistance and recent viral pandemic events have
enhanced the need for novel approaches through innovative agents that are mainly able to …

Microbial interkingdom biofilms and the quest for novel therapeutic strategies

K Van Dyck, RM Pinto, D Pully, P Van Dijck - Microorganisms, 2021 - mdpi.com
Fungal and bacterial species interact with each other within polymicrobial biofilm
communities in various niches of the human body. Interactions between these species can …

Approaches for mitigating microbial biofilm-related drug resistance: a focus on micro-and nanotechnologies

H Rao, S Choo, SR Rajeswari Mahalingam, DS Adisuri… - Molecules, 2021 - mdpi.com
Biofilms play an essential role in chronic and healthcare-associated infections and are more
resistant to antimicrobials compared to their planktonic counterparts due to their (1) …

The Membranotropic Peptide gH625 to Combat Mixed Candida albicans/Klebsiella pneumoniae Biofilm: Correlation between In Vitro Anti-Biofilm Activity and In …

A Maione, E de Alteriis, F Carraturo, S Galdiero… - Journal of Fungi, 2021 - mdpi.com
The antibiofilm activity of a gH625 analogue was investigated to determine the in vitro
inhibition and eradication of a dual-species biofilm of Candida albicans and Klebsiella …

Impact of the Peptide WMR-K on Dual-Species Biofilm Candida albicans/Klebsiella pneumoniae and on the Untargeted Metabolomic Profile

E Galdiero, MM Salvatore, A Maione, F Carraturo… - Pathogens, 2021 - mdpi.com
In recent years, the scientific community has focused on the development of new antibiotics
to address the difficulties linked to biofilm-forming microorganisms and drug-resistant …

Effect of the Combination of Levofloxacin with Cationic Carbosilane Dendron and Peptide in the Prevention and Treatment of Staphylococcus aureus Biofilms

J Fernandez, Á Martin-Serrano, N Gómez-Casanova… - Polymers, 2021 - mdpi.com
Antibiotic resistance and biofilm-related infections, persistent in conventional antimicrobial
treatment, are continuously increasing and represent a major health problem worldwide …