Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …

Subclinical inflammation has been associated with psychosis; however, it remains unknown
whether this phenomenon appears also in the premorbid phase. Therefore, we performed a …

The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …

Schizophrenia is a debilitating psychiatric illness that remains poorly understood. While the
bulk of symptomatology has classically been associated with disrupted brain functioning …

Human endogenous retroviruses (HERVs) are remnants of infections that took place several
million years ago and represent around 8% of the human genome. Despite evidence …

Background Schizophrenia is a disabling serious mental illness with unknown etiology.
Inflammatory abnormalities play an important role in the pathogenesis of the disease. Many …

Background: Cytokines have a major impact on the neurotransmitter networks that are
involved in schizophrenia pathophysiology. First Episode Psychosis (FEP) patients exhibit …

Background Immune dysfunction has been implicated in negative symptoms of
schizophrenia and also in depression. These disorders are frequently co-morbid, with some …

Background The influence of antipsychotic drugs on tumor necrosis factor-α (TNF-α) levels is
unclear, and there is no consensus on the association between TNF-α and psychotic …

BackgroundThis meta-analysis on peripheral blood compounds in drug-naïve first-episode
patients with either schizophrenia or major depressive disorder (MDD) examined which …