The role of mitochondrial dynamics in cardiovascular diseases

M Forte, L Schirone, P Ameri, C Basso… - British journal of …, 2021 - Wiley Online Library
The process of mitochondrial dynamics is emerging as a core player in cardiovascular
homeostasis. This process refers to the co‐ordinated cycles of biogenesis, fusion, fission …

The effect of resveratrol on the cardiovascular system from molecular mechanisms to clinical results

R Gal, L Deres, K Toth, R Halmosi, T Habon - International journal of …, 2021 - mdpi.com
Cardiovascular diseases are the leading causes of death worldwide. The cardioprotective
effects of natural polyphenols such as resveratrol (3, 5, 4-trihydroxystilbene) have been …

ZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT1

F Wu, W Huang, Q Tan, Y Guo, Y Cao, J Shang… - Cell Death & …, 2021 - nature.com
Among several leading cardiovascular disorders, ischemia–reperfusion (I/R) injury causes
severe manifestations including acute heart failure and systemic dysfunction. Recently, there …

Baicalin Improves Cardiac Outcome and Survival by Suppressing Drp1‐Mediated Mitochondrial Fission after Cardiac Arrest‐Induced Myocardial Damage

J Wu, H Chen, J Qin, N Chen, S Lu… - Oxidative Medicine and …, 2021 - Wiley Online Library
Myocardial injury after cardiac arrest (CA) often results in severe myocardial dysfunction and
death involving mitochondrial dysfunction. Here, we sought to investigate whether baicalin …

Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway

F Fu, C Liu, R Shi, M Li, M Zhang, Y Du… - Antioxidants & Redox …, 2021 - liebertpub.com
Aims: This study aims to explore the efficacy of punicalagin (PG) on diabetic cardiomyopathy
(DCM), with a specific focus on the mechanisms underlying the effects of PG on …

Molecular signaling to preserve mitochondrial integrity against ischemic stress in the heart: rescue or remove mitochondria in danger

JD Yu, S Miyamoto - Cells, 2021 - mdpi.com
Cardiovascular diseases are one of the leading causes of death and global health problems
worldwide, and ischemic heart disease is the most common cause of heart failure (HF). The …

Role of GTPase-dependent mitochondrial dynamins in heart diseases

J Liu, X Song, Y Yan, B Liu - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Heart function maintenance requires a large amount of energy, which is supplied by the
mitochondria. In addition to providing energy to cardiomyocytes, mitochondria also play an …

[HTML][HTML] GRK2 deletion improves the function of skin flap following ischemia-reperfusion injury by regulating Drp1

Y Wang, Y Wu, M Zhou, P Wang, J Luo… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Skin flap ischemia-reperfusion (IR) injury is the key factor to the success rate of skin
transplantation, the molecular mechanism of flap IR injury needs to be continuously …

Advances in the mechanism and treatment of mitochondrial quality control involved in myocardial infarction

C Wang, L Liu, Y Wang, D Xu - Journal of Cellular and …, 2021 - Wiley Online Library
Mitochondria are important organelles in eukaryotic cells. Normal mitochondrial
homeostasis is subject to a strict mitochondrial quality control system, including the strict …