Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foe
Swelling and the progressive destruction of articular cartilage are major characteristics of
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …
Role of microRNA shuttled in small extracellular vesicles derived from mesenchymal stem/stromal cells for osteoarticular disease treatment
E Lara-Barba, MJ Araya, CN Hill… - Frontiers in …, 2021 - frontiersin.org
Osteoarticular diseases (OD), such as rheumatoid arthritis (RA) and osteoarthritis (OA) are
chronic autoimmune/inflammatory and age-related diseases that affect the joints and other …
chronic autoimmune/inflammatory and age-related diseases that affect the joints and other …
Mechanism of miR-218-5p in autophagy, apoptosis and oxidative stress in rheumatoid arthritis synovial fibroblasts is mediated by KLF9 and JAK/STAT3 pathways
M Chen, M Li, N Zhang, W Sun… - Journal of …, 2021 - journals.sagepub.com
This study was aimed to investigate the effects of miR-218-5p on the proliferation, apoptosis,
autophagy, and oxidative stress of rheumatoid arthritis synovial fibroblasts (RASFs), and the …
autophagy, and oxidative stress of rheumatoid arthritis synovial fibroblasts (RASFs), and the …
The p53 status in rheumatoid arthritis with focus on fibroblast-like synoviocytes
P53 is a transcription factor that regulates many signaling pathways like apoptosis, cell
cycle, DNA repair, and cellular stress responses. P53 is involved in inflammatory responses …
cycle, DNA repair, and cellular stress responses. P53 is involved in inflammatory responses …
LncRNA XIST is involved in rheumatoid arthritis fibroblast-like synoviocytes by sponging miR-126-3p via the NF-κB pathway
W Liu, J Song, X Feng, H Yang, W Zhong - Autoimmunity, 2021 - Taylor & Francis
The role and mechanism of lncRNA XIST (XIST) in the development of rheumatoid arthritis
(RA) was explored in this study. RT-qPCRs were performed to detect the expression of XIST …
(RA) was explored in this study. RT-qPCRs were performed to detect the expression of XIST …
The role of miRNAs in the regulation of autophagy in autoimmune diseases
Autoimmune diseases (AD), which are classified as chronic injuries, are caused by a
specific auto-reactive reaction. The etiology of most ADs is not well understood. Meanwhile …
specific auto-reactive reaction. The etiology of most ADs is not well understood. Meanwhile …
MicroRNA-497 reduction and increase of its family member MicroRNA-424 lead to dysregulation of multiple inflammation related genes in synovial fibroblasts with …
S Wang, J Xu, Y Guo, Y Cai, X Ren, W Zhu… - Frontiers in …, 2021 - frontiersin.org
Objectives Mounting evidence has demonstrated that microRNAs (miRNAs) participate in
rheumatoid arthritis (RA). The role of highly conserved miR-15/107 family in RA has not …
rheumatoid arthritis (RA). The role of highly conserved miR-15/107 family in RA has not …
Metformin and omega-3 fish oil elicit anti-inflammatory effects via modulation of some dysregulated micro RNAs expression and signaling pathways in experimental …
Objective Rheumatoid arthritis is a progressive inflammatory disease with multiple
dysfunctional intracellular signaling pathways that necessitate new approaches for its …
dysfunctional intracellular signaling pathways that necessitate new approaches for its …
The potential importance of microRNAs as novel indicators how to manage patients with juvenile idiopathic arthritis more effectively
K Orczyk, E Smolewska - Journal of Immunology Research, 2021 - Wiley Online Library
Small, noncoding sequences of ribonucleic acid called microRNAs (miRNAs, miR) are
functioning as posttranscriptional regulators of gene expression. As they draw increasing …
functioning as posttranscriptional regulators of gene expression. As they draw increasing …
Identification of diagnostic genes and vital microRNAs involved in rheumatoid arthritis: based on data mining and experimental verification
C Ren, M Li, Y Zheng, F Wu, W Du, R Quan - PeerJ, 2021 - peerj.com
Identification of diagnostic genes and vital microRNAs involved in rheumatoid arthritis: based
on data mining and experimental verification [PeerJ] Related research Download Share X …
on data mining and experimental verification [PeerJ] Related research Download Share X …