[HTML][HTML] An update on the role of Nrf2 in respiratory disease: molecular mechanisms and therapeutic approaches
J Lee, J Jang, SM Park, SR Yang - International Journal of Molecular …, 2021 - mdpi.com
Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell
protection gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 …
protection gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 …
[HTML][HTML] Low-dose ionizing radiation as a hormetin: experimental observations and therapeutic perspective for age-related disorders
A Vaiserman, JM Cuttler, Y Socol - Biogerontology, 2021 - Springer
Hormesis is any kind of biphasic dose-response when low doses of some agents are
beneficial while higher doses are detrimental. Radiation hormesis is the most thoroughly …
beneficial while higher doses are detrimental. Radiation hormesis is the most thoroughly …
Immunomodulatory low-dose whole-lung radiation for patients with coronavirus disease 2019-related pneumonia
CB Hess, TH Nasti, VR Dhere, TJ Kleber… - International Journal of …, 2021 - Elsevier
Purpose Phase 1 clinical trials have established low-dose, whole-lung radiation therapy (LD-
RT) as safe for patients with coronavirus disease 2019 (COVID-19)-related pneumonia. By …
RT) as safe for patients with coronavirus disease 2019 (COVID-19)-related pneumonia. By …
Nrf2 activation putatively mediates clinical benefits of low-dose radiotherapy in COVID-19 pneumonia and acute respiratory distress syndrome (ARDS): Novel …
EJ Calabrese, WJ Kozumbo, R Kapoor… - Radiotherapy and …, 2021 - Elsevier
Novel mechanistic insights are discussed herein that link a single, nontoxic, low-dose
radiotherapy (LDRT) treatment (0.5–1.0 Gy) to (1) beneficial subcellular effects mediated by …
radiotherapy (LDRT) treatment (0.5–1.0 Gy) to (1) beneficial subcellular effects mediated by …
Low dose ionizing radiation and the immune response: what is the role of non-targeted effects?
A Dawood, C Mothersill, C Seymour - International Journal of …, 2021 - Taylor & Francis
Objectives This review aims to trace the historical narrative surrounding the low dose effects
of radiation on the immune system and how our understanding has changed from the …
of radiation on the immune system and how our understanding has changed from the …
Whole lung irradiation as a novel treatment for COVID-19: Interim results of an ongoing phase 2 trial in India
G Ganesan, S Ponniah, V Sundaram… - Radiotherapy and …, 2021 - Elsevier
Background and purpose The main cause of death in COVID-19 pneumonia is acute
respiratory distress syndrome which is preceded by massive cytokine release. Low-dose …
respiratory distress syndrome which is preceded by massive cytokine release. Low-dose …
Whole-lung low-dose radiation therapy (LD-RT) for non-intubated oxygen-dependent patients with COVID-19-related pneumonia receiving dexamethasone and/or …
CB Hess, TY Eng, TH Nasti, VR Dhere… - Radiotherapy and …, 2021 - Elsevier
Background Low-dose radiotherapy (LD-RT) has produced anti-inflammatory effects in both
animal models and early human trials of COVID-19-related pneumonia. The role of whole …
animal models and early human trials of COVID-19-related pneumonia. The role of whole …
[HTML][HTML] COVID-19 and low-dose radiation therapy
NE Dunlap, V van Berkel, L Cai - Radiation Medicine and Protection, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …
[HTML][HTML] Low-dose radiation therapy for COVID-19: A systematic review
SMJ Mortazavi, SF Shams, S Mohammadi… - Radiation, 2021 - mdpi.com
Simple Summary There are limited available data indicating that in oxygen-dependent
elderly patients with COVID-19-associated pneumonia, low-dose whole-lung radiation …
elderly patients with COVID-19-associated pneumonia, low-dose whole-lung radiation …
Low-dose radiation therapy for osteoarthritis and enthesopathies: a review of current data
SA Javadinia, N Nazeminezhad… - … Journal of Radiation …, 2021 - Taylor & Francis
Background Osteoarthritis (OA), the most common degenerative joint disease, is associated
with severe functional limitation and impairment of quality of life. Numerous reports have …
with severe functional limitation and impairment of quality of life. Numerous reports have …