Age-related sporadic cerebral small vessel disease (CSVD) has gained increasing attention
over the past decades because of its increasing prevalence associated with an aging …

Background and Purpose: We explored whether high-degree magnetic resonance imaging–
visible perivascular spaces in centrum semiovale (CSO) are more prevalent in cerebral …

Age-related white matter lesion (WML) is considered a manifestation of sporadic cerebral
small vessel disease and an important pathological substrate for dementia. Asia is notable …

Background The cut-off for hypertension was lowered to blood pressure (BP) over 130/80
mmHg in the 2017 American College of Cardiology/American Heart Association (ACC/AHA) …

Asymptomatic (or “silent”) manifestations of cerebral small vessel disease (CSVD) are
widely recognized through incidental findings of white matter hyperintensities (WMHs) as a …

Background Growth differentiation factor‐15 (GDF‐15) has emerged as a novel biomarker to
predict all‐cause death in community‐dwelling individuals and patients with cardiovascular …

Cerebral small vessel disease (CSVD) is one of the most prevalent pathological processes
affecting the structure and function of the smallest cerebral blood vessels. Depending on the …

Background and Purpose: This study aimed to assess the effect of baseline white matter
hyperintensities (WMH) on 1-year stroke recurrence and the functional outcome for patients …

High blood pressure (BP) is the strongest modifiable risk factor for spontaneous
intracerebral haemorrhage (ICH). International guidelines about the management of high BP …

Dementia has a complex pathophysiology which includes accumulation of protein
aggregates, progressive neuronal loss, vascular brain injury, neuroinflammation and …