Immunological responses and biomarkers for allergen-specific immunotherapy against inhaled allergens

MH Shamji, JA Layhadi, H Sharif, M Penagos… - The Journal of Allergy …, 2021 - Elsevier
Long-term efficacy that occurs with allergen immunotherapy of proven value is associated
with decreases in IgE-dependent activation of mast cells and tissue eosinophilia. This …

Basophil sensitivity reflects long‐term clinical outcome of subcutaneous immunotherapy in grass pollen‐allergic patients

JM Schmid, PA Würtzen, P Siddhuraj, P Jogdand… - Allergy, 2021 - Wiley Online Library
Background Allergic rhinoconjunctivitis is a public health problem. Allergen Immunotherapy
is an effective and safe treatment, that modifies the natural course of allergic disease and …

[HTML][HTML] Mucosal nanoemulsion allergy vaccine suppresses alarmin expression and induces bystander suppression of reactivity to multiple food allergens

M Farazuddin, JJ Landers, KW Janczak… - Frontiers in …, 2021 - frontiersin.org
We have demonstrated that intranasal immunotherapy with allergens formulated in a
nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and …

[HTML][HTML] Fungal allergic sensitisation in young rural Zimbabwean children: gut mycobiome and seroreactivity characteristics

LT Pfavayi, EN Sibanda, S Baker, M Woolhouse… - Current Research in …, 2021 - Elsevier
Background The prevalence of allergic diseases has increased over the last few decades,
with sensitisation to fungal allergens and gut microbiome dysbiosis implicated in this trend …

Intranasal delivery of allergen in a nanoemulsion adjuvant inhibits allergen‐specific reactions in mouse models of allergic airway disease

JR Baker Jr, AJ Rasky, JJ Landers… - Clinical & …, 2021 - Wiley Online Library
Background Atopic diseases are an increasing problem that involve both immediate
hypersensitivity reactions mediated by IgE and unique cellular inflammation. Many forms of …

[HTML][HTML] Сублингвальная аллергенспецифическая иммунотерапия как оптимальный и безопасный метод лечения больных с аллергопатологией

ЕМ Костина, ЭБ Белан, ЕЮ Трушина… - Практическая …, 2021 - cyberleninka.ru
В настоящее время аллергенспецифическая иммунотерапия (АСИТ) признана
наиболее эффективным способом лечения аллергических болезней. В статье …

Adaptive discrimination of antigen risk by predictive coding in immune system

K Yoshido, H Naoki - bioRxiv, 2021 - biorxiv.org
The immune system discriminates between harmful and harmless antigens based on past
experiences; however, the underlying mechanism is largely unknown. From the viewpoint of …

Real word evidence studies: Is it the way forward?

MH Shamji, RJ Boyle - Clinical & Experimental Allergy, 2021 - search.ebscohost.com
The study interestingly found that the combined use of CRD and an eDiary increased the
hypothetical AIT prescriptions, both among 18 allergy specialists and 28 general …

Investigating molecular and genetic differences in allergic rhinitis phenotypes

S Samra - 2021 - open.library.ubc.ca
Allergic rhinitis (AR) is a heterogeneous disorder that is associated with inflammation of the
upper airways. The prevalence of AR has increased rapidly in recent years, and currently …

[PDF][PDF] MASTERARBEIT/MASTER'S THESIS

D Kerekes - 2021 - phaidra.univie.ac.at
1 Abstract E. coli A0 34/86 (E coli O83; serotype O83: K24: H31) has already been used for a
long period of time as a probiotic bacterium and is commercially available as Colinfant …