[HTML][HTML] Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance

MD Manniello, A Moretta, R Salvia, C Scieuzo… - Cellular and Molecular …, 2021 - Springer
Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

The antibiotic resistome: a guide for the discovery of natural products as antimicrobial agents

C Hobson, AN Chan, GD Wright - Chemical Reviews, 2021 - ACS Publications
The use of life-saving antibiotics has long been plagued by the ability of pathogenic bacteria
to acquire and develop an array of antibiotic resistance mechanisms. The sum of these …

[HTML][HTML] Antibiotic resistance in agriculture: Perspectives on upcoming strategies to overcome upsurge in resistance

A Mann, K Nehra, JS Rana, T Dahiya - Current research in microbial …, 2021 - Elsevier
Antibiotic resistance is a massive problem rising constantly and spreading rapidly since the
past decade. The major underlying mechanism responsible for this problem is an overuse or …

[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria

Y Liu, Z Tong, J Shi, R Li, M Upton, Z Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

[HTML][HTML] Efflux pump mediated antimicrobial resistance by staphylococci in health-related environments: challenges and the quest for inhibition

A Dashtbani-Roozbehani, MH Brown - Antibiotics, 2021 - mdpi.com
The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …

[HTML][HTML] Antimicrobial Activities of Alginate and Chitosan Oligosaccharides Against Staphylococcus aureus and Group B Streptococcus

M Asadpoor, GN Ithakisiou, JPM Van Putten… - Frontiers in …, 2021 - frontiersin.org
The bacterial pathogens Streptococcus agalactiae (GBS) and Staphylococcus aureus (S.
aureus) cause serious infections in humans and animals. The emergence of antibiotic …

[HTML][HTML] Reversion of antibiotic resistance in multidrug-resistant pathogens using non-antibiotic pharmaceutical benzydamine

Y Liu, Z Tong, J Shi, Y Jia, T Deng, Z Wang - Communications Biology, 2021 - nature.com
Antimicrobial resistance has been a growing concern that gradually undermines our
tradition treatment regimens. The fact that few antibacterial drugs with new scaffolds or …

Emerging roles of glycopeptide antibiotics: Moving beyond gram-positive bacteria

Y Acharya, S Bhattacharyya, G Dhanda… - ACS Infectious …, 2021 - ACS Publications
Glycopeptides, a class of cell wall biosynthesis inhibitors, have been the antibiotics of choice
against drug-resistant Gram-positive bacterial infections. Their unique mechanism of action …

[HTML][HTML] Regulation of resistance in vancomycin-resistant enterococci: the VanRS two-component system

AA Guffey, PJ Loll - Microorganisms, 2021 - mdpi.com
Vancomycin-resistant enterococci (VRE) are a serious threat to human health, with few
treatment options being available. New therapeutics are urgently needed to relieve the …

Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria

N Zhu, C Zhong, T Liu, Y Zhu, S Gou, H Bao… - European Journal of …, 2021 - Elsevier
The increasing prevalence of antibiotic resistance in Gram-negative bacteria calls for the
discovery of novel effective therapeutic strategies urgently. Mastoparan-C (MP-C), a typical …