Regulatory T cells in autoimmunity and cancer: a duplicitous lifestyle

A Hatzioannou, A Boumpas, M Papadopoulou… - Frontiers in …, 2021 - frontiersin.org
Regulatory T (Treg) cells, possess a strategic role in the maintenance of immune
homeostasis, and their function has been closely linked to development of diverse …

From astrocytes to satellite glial cells and back: A 25 year-long journey through the purinergic modulation of glial functions in pain and more

S Ceruti - Biochemical Pharmacology, 2021 - Elsevier
Fundamental progresses have been made in pain research with a comprehensive
understanding of the neuronal pathways which convey painful sensations from the periphery …

Anti-inflammatory effects of endogenously released adenosine in synovial cells of osteoarthritis and rheumatoid arthritis patients

R Sohn, M Junker, A Meurer, F Zaucke… - International journal of …, 2021 - mdpi.com
Exogenous adenosine and its metabolite inosine exert anti-inflammatory effects in
synoviocytes of osteoarthritis (OA) and rheumatoid arthritis (RA) patients. We analyzed …

In search of a role for extracellular purine enzymes in bone function

M Zuccarini, P Giuliani, F Caciagli, R Ciccarelli… - Biomolecules, 2021 - mdpi.com
Bone is one of the major tissues that undergoes continuous remodeling throughout life, thus
ensuring both organic body growth during development and protection of internal organs as …

Dendritic Cells as a Disputed Fortress on the Tick–Host Battlefield

A Sá-Nunes, CJF Oliveira - Trends in parasitology, 2021 - cell.com
From seminal publications in the early 1970s, the world learned that dendritic cells (DCs)
are powerful and versatile antigen-presenting cells. It took a few years until the first studies …

A1 and A2A adenosine receptors play a protective role to reduce prevalence of autoimmunity following tissue damage

R Riff, O Naamani, J Mazar, YS Haviv… - Clinical & …, 2021 - academic.oup.com
Adenosine is a potent modulator that has a tremendous effect on the immune system.
Adenosine affects T cell activity, and is necessary in maintaining the T helper/regulatory T …

Adenine-based purines and related metabolizing enzymes: Evidence for their impact on tumor extracellular vesicle activities

P Di Iorio, R Ciccarelli - Cells, 2021 - mdpi.com
Extracellular vesicles (EVs), mainly classified as small and large EVs according to their
size/origin, contribute as multi-signal messengers to intercellular communications in …

[PDF][PDF] Adenine-Based Purines and Related Metabolizing Enzymes: Evidence for Their Impact on Tumor Extracellular Vesicle Activities. Cells 2021, 10, 188

P Di Iorio, R Ciccarelli - 2021 - ricerca.unich.it
Extracellular vesicles (EVs), mainly classified as small and large EVs according to their
size/origin, contribute as multi-signal messengers to intercellular communications in …

Special Issue “Adenosine Receptors as Attractive Targets in Human Diseases”

D Catarzi, F Varano, V Colotta - Pharmaceuticals, 2021 - mdpi.com
The idea of promoting this Special Issue arises from the desire to witness the
multidisciplinary efforts that are currently in progress to provide new insights into the …