Mitochondria in early forebrain development: from neurulation to mid-corticogenesis

RM Fame, MK Lehtinen - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Function of the mature central nervous system (CNS) requires a substantial proportion of the
body's energy consumption. During development, the CNS anlage must maintain its …

Gestational folate deficiency alters embryonic gene expression and cell function

RS Seelan, P Mukhopadhyay, J Philipose, RM Greene… - Differentiation, 2021 - Elsevier
Folic acid is a nutrient essential for embryonic development. Folate deficiency can cause
embryonic lethality or neural tube defects and orofacial anomalies. Folate receptor 1 (Folr1) …

[HTML][HTML] Misregulation of cell adhesion molecules in the Ciona neural tube closure mutant bugeye

HM Smith, SM Khairallah, AH Nguyen… - Developmental …, 2021 - Elsevier
Neural tube closure (NTC) is a complex multi-step morphogenetic process that transforms
the flat neural plate found on the surface of the post-gastrulation embryo into the hollow and …

A high level of KLF12 causes folic acid-resistant neural tube defects by activating the Shh signaling pathway in mice

Y Liu, Q Yuan, Z Wang, L Ding, N Kong… - Biology of …, 2021 - academic.oup.com
Although adequate periconceptional folic acid (FA) supplementation has reduced the
occurrence of pregnancies affected by neural tube defects (NTDs), the mechanisms …

Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport

X Shi, B Reinstadler, H Shah, TL To, K Byrne… - bioRxiv, 2021 - biorxiv.org
The SLC25 carrier family consists of 53 transporters that shuttle nutrients and co-factors
across mitochondrial membranes-. The family is highly redundant and their transport …

叶酸载体基因多态性与胎儿神经管缺陷.

裴娇娇, 谢江燕, 伍小莉 - Journal of International …, 2021 - search.ebscohost.com
叶酸是一组水溶性维生素(维生素B9) 的天然存在形式, 作为体内一碳单位转移酶系的辅酶,
为体内甲基化反应和核酸合成提供重要原材料, 其衍生物也是许多一碳单位转移反应的底物 …

[图书][B] An Investigation into the Molecular Mechanisms Controlling Neural Tube Closure in the Basal Chordate Ciona

HM Smith - 2021 - search.proquest.com
Neural tube closure (NTC) is a fundamental process in the development of all chordates.
During NTC, the developing central nervous system is transformed from a flat sheet of neural …

[PDF][PDF] MENINGOENCEFALOCELE OCCIPITAL: REPORTE DE UN CASO

MRCD Guartán, MDCP Paredes, M Ruth… - researchgate.net
RESUMEN INTRODUCCIÓN: El encefalocele es un tipo de malformación del tubo neural,
en donde la falta de separación del ectodermo superficial del neuroectodermo durante la …

[引用][C] Генетические аспекты нарушений фолатного цикла: связь с врожденными пороками развития

АА Гусина - Репродуктивное здоровье. Восточная Европа, 2021 - elibrary.ru
В обзоре представлены современные представления о метаболизме фолатов, а также
о распространенных полиморфизмах генов фолатного цикла и их связи с …