[HTML][HTML] Stevens–Johnson syndrome and toxic epidermal necrolysis: a review of diagnosis and management

R Frantz, S Huang, A Are, K Motaparthi - Medicina, 2021 - mdpi.com
Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases
that are characterized by widespread epidermal necrosis and sloughing of skin. They are …

Treating toxic epidermal necrolysis with systemic immunomodulating therapies: a systematic review and network meta-analysis

TY Tsai, IH Huang, YC Chao, H Li, TS Hsieh… - Journal of the American …, 2021 - Elsevier
Background Various systemic immunomodulating therapies have been used to treat toxic
epidermal necrolysis (TEN), but their efficacy remains unclear. Objective To perform a …

Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis

M Kinoshita, Y Ogawa, N Hama, I Ujiie… - Science translational …, 2021 - science.org
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening
mucocutaneous adverse drug reactions characterized by massive epidermal detachment …

[HTML][HTML] Toxic epidermal necrolysis post COVID-19 vaccination-first reported case

M Bakir, H Almeshal, R Alturki, S Obaid, A Almazroo - Cureus, 2021 - ncbi.nlm.nih.gov
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of acute,
delayed-type hypersensitivity reactions that affect the skin and the mucous membranes …

Assessment of treatment approaches and outcomes in Stevens-Johnson syndrome and toxic epidermal necrolysis: insights from a pan-European multicenter study

K Kridin, MC Brüggen, SL Chua, A Bygum… - JAMA …, 2021 - jamanetwork.com
Importance Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are
severe drug reactions associated with a high rate of mortality and morbidity. There is no …

Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians

CW Wang, W Tassaneeyakul, CB Chen… - Journal of Allergy and …, 2021 - Elsevier
Background Co-trimoxazole, a sulfonamide antibiotic, is used to treat a variety of infections
worldwide, and it remains a common first-line medicine for prophylaxis against …

[HTML][HTML] Current perspectives on severe drug eruption

J Zhang, Z Lei, C Xu, J Zhao, X Kang - Clinical Reviews in Allergy & …, 2021 - Springer
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe
drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are …

Recognition and management of severe cutaneous adverse drug reactions (including drug reaction with eosinophilia and systemic symptoms, Stevens-Johnson …

CE Owen, JM Jones - Medical Clinics, 2021 - medical.theclinics.com
Severe cutaneous adverse reactions to medications (SCARs) are dose-dependent
manifestations of hypersensitivity phenotypes. Drug reaction with eosinophilia and systemic …

Systemic therapies for Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: a SCORTEN‐based systematic review and meta‐analysis

I Torres‐Navarro, Á Briz‐Redón… - Journal of the …, 2021 - Wiley Online Library
Background The SCORTEN score is a specific predictor of mortality for patients with Stevens–
Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). There is little evidence in …

Reactive infectious mucocutaneous eruption: Mycoplasma pneumoniae‐induced rash and mucositis and other parainfectious eruptions

ML Ramien - Clinical and Experimental Dermatology, 2021 - academic.oup.com
Mycoplasma pneumoniae‐induced rash and mucositis is the most accurate diagnosis for
patients with blistering mucocutaneous disease provoked by an infection. Recent literature …