[HTML][HTML] Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G2 Arrest in Cryptococcus

S Altamirano, Z Li, MS Fu, M Ding, SR Fulton, JM Yoder… - Mbio, 2021 - Am Soc Microbiol
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response
to the host lung environment that are critical for host adaptation and subsequent disease …

Adenylyl Cyclase and Protein Kinase A Play Redundant and Distinct Roles in Growth, Differentiation, Antifungal Drug Resistance, and Pathogenicity of Candida auris

JS Kim, KT Lee, MH Lee, E Cheong, YS Bahn - mbio, 2021 - Am Soc Microbiol
Candida auris is a globally emerging multidrug-resistant fungal pathogen. Its pathogenicity-
related signaling networks are largely unknown. Here, we characterized the pathobiological …

[HTML][HTML] The role of Toll-like receptor 9 in a murine model of Cryptococcus gattii infection

EB da Silva-Junior, L Firmino-Cruz… - Scientific Reports, 2021 - nature.com
Abstract Toll-like receptor 9 (TLR9) is crucial to the host immune response against fungi,
such as Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans, but its …

[HTML][HTML] Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans

C Fu, A Davy, S Holmes, S Sun, V Yadav, A Gusa… - PLoS …, 2021 - journals.plos.org
Genome copy number variation occurs during each mitotic and meiotic cycle and it is crucial
for organisms to maintain their natural ploidy. Defects in ploidy transitions can lead to …

Host-derived Reactive Nitrogen Species mediate the Cryptococcus neoformans yeast-to-titan switch via fungal-derived superoxide

X Zhou, GE Desanti, RC May, IM Dambuza, ER Ballou - BioRxiv, 2021 - biorxiv.org
In the host lung, the human fungal pathogen Cryptococcus neoformans undergoes a
morphological switch from small haploid yeast to large polyploid titan cell, contributing to C …

Genetic and environmental influences on the evolution of virulence in the HIV-associated opportunistic human fungal pathogen Cryptococcus neoformans

Y Yu, Y Wang, L Li, X Chen, X Huang, H Liang, T Jiang… - bioRxiv, 2021 - biorxiv.org
The fungus Cryptococcus neoformans is considered the leading cause of death in
immunocompromised patients. Despite numerous investigations concerning its molecular …

[PDF][PDF] Facultad de Farmacia

L de Agustín Sierra - 2021 - docta.ucm.es
Aplicación de criterios PRISCUS, STOPP y Beers en la detección de prescripciones
potencialmente inapropiadas en el paciente ma Page 1 UNIVERSIDAD COMPLUTENSE …

[PDF][PDF] FACULTAD DE FARMACIA

TYEII EII - 2021 - docta.ucm.es
El AHCC es un producto natural descubierto en 1986 y patentado por la empresa japonesa
Amino up, que se obtiene a partir de la fermentación del micelio del hongo L. edodes. Está …