[HTML][HTML] Advances in genome editing and application to the generation of genetically modified rat models
V Chenouard, S Remy, L Tesson, S Ménoret… - Frontiers in …, 2021 - frontiersin.org
The rat has been extensively used as a small animal model. Many genetically engineered
rat models have emerged in the last two decades, and the advent of gene-specific …
rat models have emerged in the last two decades, and the advent of gene-specific …
[HTML][HTML] Proteomic insights into synaptic signaling in the brain: the past, present and future
Y Xu, X Song, D Wang, Y Wang, P Li, J Li - Molecular Brain, 2021 - Springer
Chemical synapses in the brain connect neurons to form neural circuits, providing the
structural and functional bases for neural communication. Disrupted synaptic signaling is …
structural and functional bases for neural communication. Disrupted synaptic signaling is …
[HTML][HTML] LMT USV toolbox, a novel methodological approach to place mouse ultrasonic vocalizations in their behavioral contexts—a study in female and male C57BL …
F de Chaumont, N Lemière, S Coqueran… - Frontiers in behavioral …, 2021 - frontiersin.org
Ultrasonic vocalizations (USVs) are used as a phenotypic marker in mouse models of
neuropsychiatric disorders. Nevertheless, current methodologies still require time …
neuropsychiatric disorders. Nevertheless, current methodologies still require time …
[HTML][HTML] SHANK2 mutations impair apoptosis, proliferation and neurite outgrowth during early neuronal differentiation in SH-SY5Y cells
C Unsicker, FB Cristian, M von Hahn, V Eckstein… - Scientific Reports, 2021 - nature.com
SHANK2 mutations have been identified in individuals with neurodevelopmental disorders,
including intellectual disability and autism spectrum disorders (ASD). Using CRISPR/Cas9 …
including intellectual disability and autism spectrum disorders (ASD). Using CRISPR/Cas9 …
Biological implications of genetic variations in autism spectrum disorders from genomics studies
Y Zhang, X Liu, R Guo, W Xu, Q Guo, C Hao… - Bioscience …, 2021 - portlandpress.com
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental condition
characterized by atypical social interaction and communication together with repetitive …
characterized by atypical social interaction and communication together with repetitive …
Receptores mGlu-I no MNTB modulam canais HCN e regulam a liberação de vesículas sinápticas
AMB Correa - 2021 - repositorio.ufmg.br
We examined effects of Group I metabotropic glutamate receptors on the excitability of
principal neurons in mouse medial nucleus of the trapezoid body (MNTB). These effects …
principal neurons in mouse medial nucleus of the trapezoid body (MNTB). These effects …