Overcoming barriers by local drug delivery with liposomes

SG Antimisiaris, A Marazioti, M Kannavou… - Advanced drug delivery …, 2021 - Elsevier
Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

Lipid based nanocarriers: A novel paradigm for topical antifungal therapy

S Nene, S Shah, N Rangaraj, NK Mehra… - Journal of Drug Delivery …, 2021 - Elsevier
Superficial fungal infections manifesting the skin have become prevalent today. Even though
there has been a substantial number of antifungal drugs approved for treating topical fungal …

Ethosomes and transethosomes for mangiferin transdermal delivery

M Sguizzato, F Ferrara, SS Hallan, A Baldisserotto… - Antioxidants, 2021 - mdpi.com
Mangiferin is a natural glucosyl xanthone with antioxidant and anti-inflammatory activity,
making it suitable for protection against cutaneous diseases. In this study ethosomes and …

An insight of techniques for the assessment of permeation flux across the skin for optimization of topical and transdermal drug delivery systems

S Chaturvedi, A Garg - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
The skin has been employed as a delivery route for localized as well as systemic delivery of
drugs. However, the Stratum corneum (SC) of the skin act as a main barrier for the …

Pharmacokinetic evaluation of the synergistic effect of raloxifene loaded transfersomes for transdermal delivery

S Mahmood, B Chatterjee, UK Mandal - Journal of Drug Delivery Science …, 2021 - Elsevier
The current research work involves the comparative evaluation of the synergistic potential of
transfersomes with span 80, span 85 for transdermal delivery of raloxifene hydrochloride …

Nanostructured lipid carrier to overcome stratum corneum barrier for the delivery of agomelatine in rat brain; formula optimization, characterization and brain …

S Ahmed, S Mahmood, MD Ansari, A Gull… - International Journal of …, 2021 - Elsevier
The current work attempted to achieve bypassed hepatic metabolism, controlled release,
and boosted brain distribution of agomelatine by loading in NLC and administering via …

Strategies for transdermal drug delivery against bone disorders: A preclinical and clinical update

G Sharma, M Alle, C Chakraborty, JC Kim - Journal of Controlled Release, 2021 - Elsevier
The transdermal drug delivery system is an exceptionally safe and well-tolerable therapeutic
approach that has immense potential for delivering active components against bone-related …

Ibuprofen-Loaded Chitosan–Lipid Nanoconjugate Hydrogel with Gum Arabic: Green Synthesis, Characterisation, In Vitro Kinetics Mechanistic Release Study and …

S Mahmood, SH Almurisi, K Al-Japairai, AR Hilles… - Gels, 2021 - mdpi.com
Ibuprofen is a well-known non-steroidal anti-inflammatory (NSAID) medicine that is often
used to treat inflammation in general. When given orally, it produces gastrointestinal issues …

Exploration of a transdermal nanoemulgel as an alternative therapy for postmenopausal osteoporosis

F Zakir, A Ahmad, MA Mirza, K Kohli… - Journal of Drug Delivery …, 2021 - Elsevier
The study investigated the ability of a transdermal nanoemulgel formulation to enhance the
bioavailability and anti-osteoporotic efficacy of raloxifene hydrochloride (RH) using recent …

Doe guided chitosan based nano-ophthalmic preparation against fungal keratitis

N Hassan, MA Mirza, M Aslam, S Mahmood… - Materials Today …, 2021 - Elsevier
A recent upsurge in ocular infections is a pointer towards an enhanced prevalence of
ophthalmic disorders, posing challenges for researchers globally. The caveats of …