H/ACA small ribonucleoproteins: structural and functional comparison between archaea and eukaryotes
DP Czekay, U Kothe - Frontiers in Microbiology, 2021 - frontiersin.org
During ribosome synthesis, ribosomal RNA is modified through the formation of many
pseudouridines and methylations which contribute to ribosome function across all domains …
pseudouridines and methylations which contribute to ribosome function across all domains …
Dyskerin: an essential pseudouridine synthase with multifaceted roles in ribosome biogenesis, splicing, and telomere maintenance
A Garus, C Autexier - Rna, 2021 - rnajournal.cshlp.org
Dyskerin and its homologs are ancient and conserved enzymes that catalyze the most
common post-transcriptional modification found in cells, pseudouridylation. The resulting …
common post-transcriptional modification found in cells, pseudouridylation. The resulting …
NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis
The PAQosome is a large complex composed of the HSP90/R2TP chaperone and a
prefoldin-like module. It promotes the biogenesis of cellular machineries but it is unclear …
prefoldin-like module. It promotes the biogenesis of cellular machineries but it is unclear …
INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication
U Dixit, S Bhutoria, X Wu, L Qiu, M Spira… - Nature …, 2021 - nature.com
Abstract INI1/SMARCB1 binds to HIV-1 integrase (IN) through its Rpt1 domain and exhibits
multifaceted role in HIV-1 replication. Determining the NMR structure of INI1-Rpt1 and …
multifaceted role in HIV-1 replication. Determining the NMR structure of INI1-Rpt1 and …
SUMOylation-and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization
DE MacNeil, P Lambert-Lanteigne, J Qin… - … and Cellular Biology, 2021 - Taylor & Francis
The nuclear and subnuclear compartmentalization of the telomerase-associated protein and
H/ACA ribonucleoprotein component dyskerin is an important although incompletely …
H/ACA ribonucleoprotein component dyskerin is an important although incompletely …
Regulation of human telomerase RNA biogenesis and localization
J Qin, C Autexier - RNA biology, 2021 - Taylor & Francis
Maintenance of telomeres is essential for genome integrity and replicative capacity in
eukaryotic cells. Telomerase, the ribonucleoprotein complex that catalyses telomere …
eukaryotic cells. Telomerase, the ribonucleoprotein complex that catalyses telomere …
Mutations-und Expressionsanalyse des FOXP1-Gens bei der akuten myeloischen Leukämie des Erwachsenen
M Schlegel - 2021 - oparu.uni-ulm.de
Die akute myeloische Leukämie (AML) ist eine klonale Erkrankung der hämatopoetischen
Stammzelle, die durch eine Akquisition diverser genetischer Alterationen charakterisiert ist …
Stammzelle, die durch eine Akquisition diverser genetischer Alterationen charakterisiert ist …
[图书][B] Binding of in vitro reconstituted snR30 Ribonucleoprotein to Ribosomal RNA
TJ Vos - 2021 - search.proquest.com
The creation of eukaryotic ribosomes is a complex process involving hundreds of assembly
factors, including the small nucleolar RNA snR30. Through interacting with the unprocessed …
factors, including the small nucleolar RNA snR30. Through interacting with the unprocessed …
[图书][B] Rna-Binding Proteins in Transcription and Genome Integrity
C Pederiva - 2021 - search.proquest.com
For decades, it was believed that RNA was merely an intermediate step between DNA and
protein effectors. It is now appreciated that RNA is an extremely versatile molecule that …
protein effectors. It is now appreciated that RNA is an extremely versatile molecule that …