Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Polysaccharide nanoparticles: From fabrication to applications
A Plucinski, Z Lyu, BVKJ Schmidt - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …
recent years, which is due to their remarkable features such as biocompatibility …
Chemical and physical Chitosan modification for designing enzymatic industrial biocatalysts: How to choose the best strategy?
YL Nunes, FL de Menezes, IG de Sousa… - International Journal of …, 2021 - Elsevier
Chitosan is one of the most abundant natural polymer worldwide, and due to its inherent
characteristics, its use in industrial processes has been extensively explored. Because it is …
characteristics, its use in industrial processes has been extensively explored. Because it is …
Chitosan as a machine for biomolecule delivery: A review
Z Mohammadi, M Eini, A Rastegari, MR Tehrani - Carbohydrate Polymers, 2021 - Elsevier
The major role of biomolecules in treatment of different diseases has been proven by
several studies. However, the main drawback in successful treatment by these molecules is …
several studies. However, the main drawback in successful treatment by these molecules is …
Metal-organic frameworks for simultaneous gene and small molecule delivery in vitro and in vivo
A Ringaci, AV Yaremenko, KG Shevchenko… - Chemical Engineering …, 2021 - Elsevier
Nanoparticles based on metal–organic frameworks (nMOF) became one of the most
promising class of drug delivery vehicles due to their ability to transport a great range of …
promising class of drug delivery vehicles due to their ability to transport a great range of …
Materials for improving immune cell transfection
Chimeric antigen receptor T cell (CAR‐T) therapy holds great promise for preventing and
treating deadly diseases such as cancer. However, it remains challenging to transfect and …
treating deadly diseases such as cancer. However, it remains challenging to transfect and …
Novel perspectives towards RNA-based nano-theranostic approaches for cancer management
In the fight against cancer, early diagnosis is critical for effective treatment. Traditional
cancer diagnostic technologies, on the other hand, have limitations that make early …
cancer diagnostic technologies, on the other hand, have limitations that make early …
Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19
In 2019, a novel type of coronavirus emerged in China called SARS-COV-2, known COVID-
19, threatens global health and possesses negative impact on people's quality of life …
19, threatens global health and possesses negative impact on people's quality of life …
Nucleic acids based polyelectrolyte complexes: Their complexation mechanism, morphology, and stability
YH Kim, K Lee, S Li - Chemistry of Materials, 2021 - ACS Publications
Nucleic acids are a special class of negatively charged polymers, and they can complex with
cationic small molecules and polymers to form polyelectrolyte complexes of rich …
cationic small molecules and polymers to form polyelectrolyte complexes of rich …
Targeting dual gene delivery nanoparticles overcomes immune checkpoint blockade induced adaptive resistance and regulates tumor microenvironment for improved …
Y Feng, J Wu, J Chen, L Lin, S Zhang, Z Yang, P Sun… - Nano Today, 2021 - Elsevier
Despite the unparalleled tumor growth inhibition and significantly prolonged survival
achieved by immune checkpoint blockade (ICB) therapy, more and more adaptive …
achieved by immune checkpoint blockade (ICB) therapy, more and more adaptive …