The mechanism of drug nephrotoxicity and the methods for preventing kidney damage

E Kwiatkowska, L Domański, V Dziedziejko… - International Journal of …, 2021 - mdpi.com
Acute kidney injury (AKI) is a global health challenge of vast proportions, as approx. 13.3%
of people worldwide are affected annually. The pathophysiology of AKI is very complex, but …

Onconephrology: the intersections between the kidney and cancer

MH Rosner, KD Jhaveri, BA McMahon… - CA: a cancer journal …, 2021 - Wiley Online Library
Onconephrology is a new subspecialty of nephrology that recognizes the important
intersections of kidney disease with cancer. This intersection takes many forms and includes …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

[HTML][HTML] Acute kidney injury in patients treated with immune checkpoint inhibitors

S Gupta, SAP Short, ME Sise, JM Prosek… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI) has
emerged as an important toxicity among patients with cancer. Methods We collected data on …

A multi-center study on safety and efficacy of immune checkpoint inhibitors in cancer patients with kidney transplant

N Murakami, P Mulvaney, M Danesh, A Abudayyeh… - Kidney international, 2021 - Elsevier
Immune checkpoint inhibitors (ICIs) are widely used for various malignancies. However,
their safety and efficacy in patients with a kidney transplant have not been defined. To …

[HTML][HTML] A systematic review of immune checkpoint inhibitor–associated glomerular disease

A Kitchlu, KD Jhaveri, S Wadhwani… - Kidney international …, 2021 - Elsevier
Introduction Immune checkpoint inhibitors (ICIs) are increasingly used to treat cancers.
Kidney immune-related adverse events (IRAEs) are now well recognized, with the incidence …

Safety and efficacy of the rechallenge of immune checkpoint inhibitors after immune-related adverse events in patients with cancer: a systemic review and meta …

Q Zhao, J Zhang, L Xu, H Yang, N Liang… - Frontiers in …, 2021 - frontiersin.org
Introduction Little evidence exists on the safety and efficacy of the rechallenge of immune
checkpoint inhibitors (ICIs) after immune-related adverse events (irAEs) in patients with …

Renal adverse effects of immune checkpoints inhibitors in clinical practice: ImmuNoTox study

M Espi, C Teuma, E Novel-Catin, D Maillet… - European Journal of …, 2021 - Elsevier
Abstract Background/objectives Acute Kidney Injury (AKI), induced by Checkpoint Inhibitors
therapies (CPI-induced AKI), is an uncommon but severe Immune-Related Adverse Event …

[HTML][HTML] Biomarkers, clinical features, and rechallenge for immune checkpoint inhibitor renal immune-related adverse events

B Isik, MP Alexander, S Manohar, L Vaughan… - Kidney International …, 2021 - Elsevier
Introduction Immune checkpoint inhibitors (ICIs) are effective in treating several cancers;
however, acute kidney injury (AKI) can occur as part as an immune-related adverse event …

Renal cell cancer and chronic kidney disease

DL Saly, MS Eswarappa, SE Street… - Advances in chronic …, 2021 - Elsevier
The association between chronic kidney disease (CKD) and renal cell carcinoma (RCC) is
bidirectional and multifactorial. Risk factors such as hypertension, diabetes mellitus, obesity …