Mechanisms of Invasion in Glioblastoma: Extracellular Matrix, Ca2+ Signaling, and Glutamate

JS So, H Kim, KS Han - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Glioblastoma (GBM) is the most common and malignant form of primary brain tumor with a
median survival time of 14–16 months in GBM patients. Surgical treatment with …

[HTML][HTML] Mechanosensitive ion channels in cell migration

BC Coutino, R Mayor - Cells & Development, 2021 - Elsevier
Cellular processes are initiated and regulated by different stimuli, including mechanical
forces. Cell membrane mechanosensors represent the first step towards the conversion of …

Deciphering the Role of Ca2+ Signalling in Cancer Metastasis: From the Bench to the Bedside

A Alharbi, Y Zhang, J Parrington - Cancers, 2021 - mdpi.com
Simple Summary Ca2+ dyshomeostasis is implicated in several key pathophysiological
processes attributed to cancer metastasis biology. Here, we decipher the role of intracellular …

Ca2+ Signaling as the Untact Mode during Signaling in Metastatic Breast Cancer

D Lee, JH Hong - Cancers, 2021 - mdpi.com
Simple Summary Intracellular Ca2+ signaling is a critical factor in breast cancer metastasis.
In the proliferation stage, increases in intracellular Ca2+ concentration through voltage …

[HTML][HTML] Reprint of: Mechanosensitive ion channels in cell migration

BC Coutiño, R Mayor - Cells & Development, 2021 - Elsevier
Cellular processes are initiated and regulated by different stimuli, including mechanical
forces. Cell membrane mechanosensors represent the first step towards the conversion of …

Identifying antagonist drugs for TRPM8 ion channel as candidates for repurposing

F Jahanfar - 2021 - usiena-air.unisi.it
Even though it is confirmed that ion channels are at the centre of many diseases, approved
drugs are only available for small percentage of these proteins, and yet many pathologically …

[PDF][PDF] Deciphering the Role of Ca2+ Signalling in Cancer Metastasis: From the Bench to the Bedside. Cancers 2021, 13, 179

A Alharbi, Y Zhang, J Parrington - 2021 - pdfs.semanticscholar.org
Metastatic cancer is one of the major causes of cancer-related mortalities. Metastasis is a
complex, multi-process phenomenon, and a hallmark of cancer. Calcium (Ca2+) is a …