Advances in lipid extraction methods—a review

RK Saini, P Prasad, X Shang, YS Keum - International Journal of …, 2021 - mdpi.com
Extraction of lipids from biological tissues is a crucial step in lipid analysis. The selection of
appropriate solvent is the most critical factor in the efficient extraction of lipids. A mixture of …

Plasmalogens and chronic inflammatory diseases

JC Bozelli Jr, S Azher, RM Epand - Frontiers in physiology, 2021 - frontiersin.org
It is becoming widely acknowledged that lipids play key roles in cellular function, regulating
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …

The molecular basis of predicting atherosclerotic cardiovascular disease risk

M Nayor, KJ Brown, RS Vasan - Circulation research, 2021 - Am Heart Assoc
Atherosclerotic cardiovascular disease (ASCVD) proceeds through a series of stages:
initiation, progression (or regression), and complications. By integrating known biology …

Lipid metabolite biomarkers in cardiovascular disease: Discovery and biomechanism translation from human studies

P McGranaghan, JA Kirwan, MA Garcia-Rivera… - Metabolites, 2021 - mdpi.com
Lipids represent a valuable target for metabolomic studies since altered lipid metabolism is
known to drive the pathological changes in cardiovascular disease (CVD). Metabolomic …

Coronavirus-induced host cubic membranes and lipid-related antiviral therapies: A focus on bioactive plasmalogens

Y Deng, A Angelova - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Coronaviruses have lipid envelopes required for their activity. The fact that coronavirus
infection provokes the formation of cubic membranes (CM)(denoted also as convoluted …

Plasma metabolomic profiling in subclinical atherosclerosis: the Diabetes Heart Study

PA Chevli, BI Freedman, FC Hsu, J Xu… - Cardiovascular …, 2021 - Springer
Background Incidence rates of cardiovascular disease (CVD) are increasing, partly driven
by the diabetes epidemic. Novel prediction tools and modifiable treatment targets are …

Lysophosphatidylcholine induces oxidative stress in human endothelial cells via NOX5 activation–implications in atherosclerosis

JF Da Silva, JV Alves, JA Silva-Neto, RM Costa… - Clinical …, 2021 - portlandpress.com
Objective: The mechanisms involved in NOX5 activation in atherosclerotic processes are not
completely understood. The present study tested the hypothesis that …

Plasmalogen replacement therapy

JC Bozelli Jr, RM Epand - Membranes, 2021 - mdpi.com
Plasmalogens, a subclass of glycerophospholipids containing a vinyl-ether bond, are one of
the major components of biological membranes. Changes in plasmalogen content and …

[HTML][HTML] A plasma lipid signature predicts incident coronary artery disease

F Ottosson, PE Khoonsari, MJ Gerl, K Simons… - International Journal of …, 2021 - Elsevier
Background Dyslipidemia is a hallmark of cardiovascular disease but is characterized by
crude measurements of triglycerides, HDL-and LDL cholesterol. Lipidomics enables more …

Shark liver oil supplementation enriches endogenous plasmalogens and reduces markers of dyslipidemia and inflammation

S Paul, AAT Smith, K Culham, KA Gunawan… - Journal of lipid …, 2021 - ASBMB
Plasmalogens are membrane glycerophospholipids with diverse biological functions.
Reduced plasmalogen levels have been observed in metabolic diseases; hence, increasing …