An updated review on synthetic cathinones

J Soares, VM Costa, ML Bastos, F Carvalho… - Archives of …, 2021 - Springer
Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk.(khat), is
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …

Chemical classification of new psychoactive substances (NPS)

F Zapata, JM Matey, G Montalvo, C García-Ruiz - Microchemical Journal, 2021 - Elsevier
This work comprehensively reviews some fundamental concepts about drugs, especially
focusing on new psychoactive substances (NPS), and their typical classifications based on …

[PDF][PDF] Analytical challenges for identification of new psychoactive substances: a literature-based study for seized drugs

A Bruni, C Rodrigues, C dos Santos… - Brazilian Journal of …, 2021 - kar.kent.ac.uk
Correct identification of substances is essential to understand drug use and trafficking trends
and guide measures for harm reduction and treatment. Two steps are needed to verify the …

From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3, 4-DMMC

R Roque Bravo, H Carmo, MJ Valente, JP Silva… - Archives of …, 2021 - Springer
Synthetic cathinones are among the most popular new psychoactive substances, being
abused for their stimulant properties, which are similar to those of amphetamine and 3, 4 …

S-(+)-Pentedrone and R-(+)-methylone as the most oxidative and cytotoxic enantiomers to dopaminergic SH-SY5Y cells: Role of MRP1 and P-gp in cathinones …

B Silva, A Palmeira, R Silva, C Fernandes… - Toxicology and Applied …, 2021 - Elsevier
Cathinone derivatives are the most representative group within new drugs market, which
have been described as neurotoxic. Since cathinones, as pentedrone and methylone, are …

Can NMR spectroscopy discriminate between NPS amphetamines and cathinones? An evaluation by in silico studies and chemometrics

CHP Rodrigues, VBP Leite, AT Bruni - Chemometrics and Intelligent …, 2021 - Elsevier
The use of new psychoactive substances (NPS) has become a problem that affects many
countries. Because new chemical structures appear frequently and reliable reference data …

Structure assignment of seized products containing cathinone derivatives using high resolution analytical techniques

JL Gonçalves, VL Alves, J Aguiar, MJ Caldeira… - Metabolites, 2021 - mdpi.com
The innovation of the new psychoactive substances (NPS) market requires the rapid
identification of new substances that can be a risk to public health, in order to reduce the …

Development of a sensitive MEKC‐LIF method for synthetic cathinones analysis

P Emonts, AC Servais, E Ziemons, P Hubert… - …, 2021 - Wiley Online Library
Synthetic cathinones are phenylalkylamine compounds related to natural cathinone from
Catha edulis leaves. Due to their sympathomimetic effects comparable to common illicit …

Acute MDPV binge paradigm on mice emotional behavior and glial signature

M Campeão, L Fernandes, IR Pita, C Lemos, SF Ali… - Pharmaceuticals, 2021 - mdpi.com
3, 4-Methylenedioxypyrovalerone (MDPV), a widely available synthetic cathinone, is a
popular substitute for classical controlled drugs of abuse, such as methamphetamine …

Novas substâncias psicoativas: catinonas sintéticas

K Baranyuk - 2021 - repositorio.ul.pt
O consumo de substâncias psicoativas é uma realidade que remonta há vários séculos.
Mais recentemente, já no século XX, os Estados, cientes dos perigos decorrentes do …