Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

S Bandari, D Nyavanandi, N Dumpa… - Advanced drug delivery …, 2021 - Elsevier
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …

Hot-melt extrusion: a roadmap for product development

MF Simões, RMA Pinto, S Simões - AAPS PharmSciTech, 2021 - Springer
Hot-melt extrusion has found extensive application as a feasible pharmaceutical
technological option over recent years. HME applications include solubility enhancement …

Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industry

G Yan, Z Cao, D Devine, M Penning, NM Gately - Polymers, 2021 - mdpi.com
Hot melt extrusion offers an efficient way of increasing the solubility of a poorly soluble drug.
Shellac has potential as a pharmaceutical matrix polymer that can be used in this extrusion …

Formulation and in vivo evaluation of a solid self-emulsifying drug delivery system using oily liquid tocotrienols as model active substance

YZ Lee, EK Seow, SC Lim, KH Yuen… - Pharmaceutics, 2021 - mdpi.com
Self-emulsifying drug delivery systems (SEDDS) can improve the oral bioavailability of
poorly water-soluble drugs. Solid self-emulsifying drug delivery systems (s-SEDDS) offer …

Aqueous and pH dependent coacervation method for taste masking of paracetamol via amorphous solid dispersion formation

B Al-Kasmi, MHDB Alsirawan, A Paradkar… - Scientific Reports, 2021 - nature.com
Taste masking of paracetamol was achieved by preparing amorphous solid dispersion
(ASD) using modified coacervation method. The method is based on dissolving the drug and …

Improving solubility and supersaturation of poorly soluble drugs using solid dispersions based on natural polymers and mixtures thereof

DN Kapote - 2021 - bonndoc.ulb.uni-bonn.de
The poor solubility of existing drug substances and new chemical entities is a problem in
modern pharmaceutical development. There are various strategies to overcome the …