Dystonia is a clinically, genetically, and biologically heterogeneous hyperkinetic movement
disorder caused by the dysfunctional activity of neural circuits involved in motor control. Our …

Major depressive disorder (MDD) is the foremost cause of global disability, being
responsible for enormous personal, societal, and economical costs. Importantly, existing …

An impairment of long-term synaptic plasticity is considered as a peculiar endophenotype of
distinct forms of dystonia, a common, disabling movement disorder. Among the few …

Stimulatory coupling of dopamine D1 (D1R) and adenosine A2A receptors (A2AR) to
adenylyl cyclase within the striatum is mediated through a specific Gαolfβ2γ7 heterotrimer to …

Depression, rapid eye movement (REM) sleep behavior disorder, and altered olfaction are
often present in Parkinson's disease. Our previous studies demonstrated the role of the …

Rhythmic activity is a type of brain activity that involves repeated depolarization of neuronal
networks, which is associated with a number of important brain functions, including the …

Adult neurogenesis is a complex process, describing the generation of newly born,
immature neurons in the mature, adult brain and has yet only been described in two specific …