Non-coding RNAs and potential therapeutic targeting in cancer
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
A nuclear long non-coding RNA LINC00618 accelerates ferroptosis in a manner dependent upon apoptosis
Z Wang, X Chen, N Liu, Y Shi, Y Liu, L Ouyang, S Tam… - Molecular Therapy, 2021 - cell.com
Ferroptosis is primarily caused by intracellular iron catalytic activity and lipid peroxidation.
The potential interplay between ferroptosis and apoptosis remains poorly understood. Here …
The potential interplay between ferroptosis and apoptosis remains poorly understood. Here …
Functional long non-coding RNAs in hepatocellular carcinoma
C Xie, SY Li, JH Fang, Y Zhu, JE Yang - Cancer Letters, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is a prevalent human malignancy with high morbidity
worldwide. Hepatocarcinogenesis is a complex multistep process, and its underlying …
worldwide. Hepatocarcinogenesis is a complex multistep process, and its underlying …
The involvement of long non-coding RNAs in bone
C Aurilia, S Donati, G Palmini, F Miglietta… - International journal of …, 2021 - mdpi.com
A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone
formation and resorption, pathological conditions affecting the bone may arise. In recent …
formation and resorption, pathological conditions affecting the bone may arise. In recent …
[HTML][HTML] Long non-coding RNAs: potential biomarkers and targets for hepatocellular carcinoma therapy and diagnosis
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
worldwide. Increasing studies showed that long non-coding RNAs (lncRNAs), a novel class …
worldwide. Increasing studies showed that long non-coding RNAs (lncRNAs), a novel class …
Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation
Background Disruption of DNA methylation (DNAm) is one of the key signatures of cancer,
however, detailed mechanisms that alter the DNA methylome in cancer remain to be …
however, detailed mechanisms that alter the DNA methylome in cancer remain to be …
The impact of long non-coding RNAs in the pathogenesis of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is among the utmost deadly human malignancies. This
type of cancer has been associated with several environmental, viral, and lifestyle risk …
type of cancer has been associated with several environmental, viral, and lifestyle risk …
LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells
M Xiong, M Wu, D Peng, W Huang, Z Chen, H Ke… - Cell death & …, 2021 - nature.com
Long non-coding RNA (lncRNA) DANCR has been reported to participate in key processes
such as stem cell differentiation and tumorigenesis. In a high throughput screening for …
such as stem cell differentiation and tumorigenesis. In a high throughput screening for …
Comprehensive analysis of partial epithelial mesenchymal transition‐related genes in hepatocellular carcinoma
Y Lei, W Yan, Z Lin, J Liu, D Tian… - Journal of Cellular and …, 2021 - Wiley Online Library
Increasing evidence has revealed that cancer cells undergoing an intermediate state, partial
epithelial mesenchymal transition (p‐EMT), tend to metastasize rather than complete EMT …
epithelial mesenchymal transition (p‐EMT), tend to metastasize rather than complete EMT …
[HTML][HTML] Non-coding natural antisense transcripts: Analysis and application
JC Krappinger, L Bonstingl, K Pansy, K Sallinger… - Journal of …, 2021 - Elsevier
Non-coding natural antisense transcripts (ncNATs) are regulatory RNA sequences that are
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …