Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy
in the form of heat. These thermogenic fat cells were originally considered to function solely …

Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

Obesity is the most common cause of insulin resistance, and the current obesity epidemic is
driving a parallel rise in the incidence of T2DM. It is now widely recognized that chronic …

The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …

Overnutrition causes obesity, a global health problem without any effective therapy. Obesity
is characterized by low-grade inflammation, which predisposes individuals to metabolic …

Brown adipose tissue (BAT) has been encouraged as a potential treatment for obesity and
comorbidities due to its thermogenic activity capacity and contribution to energy expenditure …

IL-17 was discovered nearly 30 yr ago, but it has only been recently appreciated that a key
function of this cytokine is to orchestrate cellular and organismal metabolism. Indeed …

Precise regulation of circulating glucose is crucial for human health and ensures a sufficient
supply to the brain, which relies almost exclusively on glucose for metabolic energy …

While beige adipocytes have been found to associate with dense sympathetic neurites in
mouse inguinal subcutaneous white fat (iWAT), little is known about when and how this …

Non‐neuronal cholinergic signaling, mediated by acetylcholine, plays important roles in
physiological processes including inflammation and immunity. Our group first discovered …