The evolution of commercial drug delivery technologies

AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Cell primitive-based biomimetic functional materials for enhanced cancer therapy

GF Luo, WH Chen, X Zeng, XZ Zhang - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell primitive-based functional materials that combine the advantages of natural substances
and nanotechnology have emerged as attractive therapeutic agents for cancer therapy. Cell …

Advancing to the era of cancer immunotherapy

Y Wang, M Wang, HX Wu, RH Xu - Cancer Communications, 2021 - Wiley Online Library
Cancer greatly affects the quality of life of humans worldwide and the number of patients
suffering from it is continuously increasing. Over the last century, numerous treatments have …

Nanotechnology-enhanced immunotherapy for metastatic cancer

P Zhang, J Meng, Y Li, C Yang, Y Hou, W Tang… - The Innovation, 2021 - cell.com
A vast majority of cancer deaths occur as a result of metastasis. Unfortunately, effective
treatments for metastases are currently lacking due to the difficulty of selectively targeting …

Cell‐based delivery systems: emerging carriers for immunotherapy

Z Li, Y Wang, Y Ding, L Repp… - Advanced Functional …, 2021 - Wiley Online Library
Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

Target reprogramming lysosomes of CD8+ T cells by a mineralized metal–organic framework for cancer immunotherapy

Q Zhao, Z Gong, Z Li, J Wang, J Zhang… - Advanced …, 2021 - Wiley Online Library
T cell immunotherapy holds significant challenges in solid tumors, mainly due to the T cells'
low activation and the decreased synthesis–release of therapeutic proteins, including …

Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles

J Qi, F Jin, Y You, Y Du, D Liu, X Xu, J Wang… - Nature …, 2021 - nature.com
Some specific chemotherapeutic drugs are able to enhance tumor immunogenicity and
facilitate antitumor immunity by inducing immunogenic cell death (ICD). However, tumor …

[HTML][HTML] Nanotechnology shaping stem cell therapy: Recent advances, application, challenges, and future outlook

Y Dong, X Wu, X Chen, P Zhou, F Xu… - Biomedicine & …, 2021 - Elsevier
Currently, stem cell nanotechnology is one of the novel and exciting fields. Certain
experimental studies conducted on the interaction of stem cells with nanostructures or …

Membrane engineering of cell membrane biomimetic nanoparticles for nanoscale therapeutics

M Zhang, S Cheng, Y Jin, N Zhang… - Clinical and …, 2021 - Wiley Online Library
In recent years, cell membrane camouflaging technology has emerged as an important
strategy of nanomedicine, and the modification on the membranes is also a promising …